NOAEL Studies
Cosmetic Ingredient
Potassium Caroate NOAEL Studies
INCI: POTASSIUM CAROATE
CAS: 70693-62-8
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
NTP_ICE_acute_inhalation 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_inhalation | LC50 | >5 | mg/L | - | Inhalation | Duration=4 hr | In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity | sheet=Data; excel_row=3814; Record_ID=acute_inhalation_2970; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID701015635; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=5; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/3/3/?documentUUID=29309eb0-2dcf-4a3f-ac18-61f79e4289ac; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID701015635 |
ToxValDB_ECHA_IUCLID 7 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LEL | =1250 | mg/m3 | Rat | inhalation | - | acute | GUIDELINE=OECD Guideline 403 (Acute Inhalation Toxicity); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059759e4b063812d6fa6de; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/3/3?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID_dup_Acute Toxicity Inhalation_15796338_15796339_15796340:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6e766ca5ebded5e991d50ab62e6521e9 |
| ToxValDB_ECHA_IUCLID | LEL | =2000 | mg/kg bw/day | Rat | dermal | acute; 24 hours | acute | GUIDELINE=OECD Guideline 402 (Acute Dermal Toxicity)|EU Method B.3 (Acute Toxicity (Dermal)); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61a60e4b096bca876a8e3; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/3/4?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID:15793706:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_41e602e33714f0d3e942e14b13e29b62 |
| ToxValDB_ECHA_IUCLID | LOAEL | =10.1 | mg/m3 | Rat | inhalation | short-term; 2 weeks | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/6/3?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829490_15829491:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9631ba840911069f504fa1df35ecb629 |
| ToxValDB_ECHA_IUCLID | LOAEL | =600 | mg/kg bw/day | Rat | oral | chronic; 91 days | chronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaed5e4b0a7c65d1cb229; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/6/2?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15840760_15840761:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_24b5e3a8f22e1a7d60f7eac6325e2ec6 |
| ToxValDB_ECHA_IUCLID | NOAEL | =200 | mg/kg bw/day | Rat | oral | chronic; 91 days | chronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaed5e4b0a7c65d1cb229; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/6/2?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15840760_15840761:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_629ac0f294fd9dfbb764ca6b87d5928c |
| ToxValDB_ECHA_IUCLID | NOEL | =1.4 | mg/m3 | Rat | inhalation | short-term; 2 weeks | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/6/3?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Inhalation_15829490_15829491:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_dd6f0c97b8052aed6b3985ab79e08967 |
| ToxValDB_ECHA_IUCLID | NOEL | >1000 | mg/kg bw/day | Rat | oral | short-term; 14 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cba9e4b0a7c65d22710e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15990/7/6/2?documentUUID=21bdeeec-5b24-4144-8223-d70d6288a3d9; YEAR=2020; ORIGINAL_YEAR=2020; STUDY_GROUP=ECHA IUCLID:15843562:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2a94de88c1b0f3d340a1affccc7d77c4 |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL local | =0.112 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634289:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_57f3167e2353853765f3c7060f504fe0 |