Is Polyglyceryl-3 PCA safe in cosmetics?
Polyglyceryl-3 PCA has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Polyglyceryl-3 PCA
INCI: POLYGLYCERYL-3 PCA
Polyglyceryl-3 PCA (CAS Not assigned (ester of pyrrolidone carboxylic acid and polyglycerin-3)) is a cosmetic cosmetic ingredient functioning as Humectant; skin-conditioning agent. PCA is pyroglutamic acid, a natural. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not assigned (ester of pyrrolidone carboxylic acid and polyglycerin-3)
View industrial chemical safety profile →
Function
Humectant; skin-conditioning agent. PCA is pyroglutamic acid, a natural moisturizing factor component.
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA: no specific restrictions; not in the CIR polyglyceryl fatty acid ester group review as PCA is not a fatty acid.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polyglyceryl-3 PCA.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Polyglyceryl-3 PCA.
Frequently Asked Questions
Is Polyglyceryl-3 PCA allowed in the EU?
Polyglyceryl-3 PCA EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglyceryl-3 PCA do in cosmetics?
Polyglyceryl-3 PCA functions as: Humectant; skin-conditioning agent. PCA is pyroglutamic acid, a natural moisturizing factor component.. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (ester of pyrrolidone carboxylic acid and polyglycerin-3).
Compliance Tools
Check Polyglyceryl-3 PCA compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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