Is Polydecene safe in cosmetics?
Polydecene has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 5 toxicological study endpoint(s) are available in our database.
Polydecene
INCI: POLYDECENE
Polydecene (CAS 68037-01-4) is a cosmetic cosmetic ingredient functioning as Emollient; skin conditioning agent. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68037-01-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Polydecene is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Emollient; skin conditioning agent
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel: Safe as used in cosmetics. No FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Polydecene.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Polydecene. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | chronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =4159.4 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =4619.9 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =6245 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
| NOAEL | =6771 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Fragrance
Softener and conditioner
Solvent
Expert Verdict
Expert safety assessment and concern-level summary for Polydecene.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Polydecene by CAS number or substance name.
Studies
5
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
6771 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Chemical Function
Solvent
Softener and conditioner
Deodorizer
Fragrance
Regulatory Lists
Europe; Personal care - make-up and related
Europe; Personal care - make-up and related
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Polydecene allowed in the EU?
Polydecene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polydecene do in cosmetics?
Polydecene functions as: Emollient; skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 68037-01-4.
What is the NOAEL for Polydecene?
The NOAEL (No Observed Adverse Effect Level) for Polydecene is =1000 mg/kg bw/day based on a chronic study via oral route in Rat. A total of 5 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Polydecene used outside cosmetics?
Polydecene also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Polydecene have different safety status in cosmetics vs industrial chemicals?
Polydecene is classified GHS Danger (H304) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Polydecene compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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