NOAEL Studies Cosmetic Ingredient

Polybutene NOAEL Studies

INCI: POLYBUTENE

CAS: 9003-28-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEC =1000 mg/m3 Rat inhalation acute; 6 hours acute QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/1291/7/6/3?documentUUID=88b21beb-56ac-4181-9abd-66af936acc0f; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID:15829457:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c32b24c6faf2ffdc7326a5101eb5129a
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c95fe4b0a7c65d21cb6d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/1291/7/9/2?documentUUID=88b21beb-56ac-4181-9abd-66af936acc0f; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855261_15855606_15856113_15856232_15856392_15856778:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b4947881c9fce820d2c8da2e8757181d
ToxValDB_ECHA_IUCLID NOEL =300 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c96ce4b0a7c65d21cc86; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/1291/7/9/2?documentUUID=88b21beb-56ac-4181-9abd-66af936acc0f; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855261_15855606_15856113_15856232_15856392_15856778:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_83ee96f123fbbb0b63c1626c69ba3646