Is Poloxamer 403 safe in cosmetics?
Poloxamer 403 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Poloxamer 403
INCI: POLOXAMER 403
Poloxamer 403 (CAS 9003-11-6 (generic for all Poloxamers)) is a cosmetic cosmetic ingredient functioning as Surfactant – Cleansing; Surfactant – Emulsifying. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9003-11-6 (generic for all Poloxamers) →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant – Cleansing; Surfactant – Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
FDA indirect food additive; CIR assessed as safe as used (2008 final report)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Poloxamer 403.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Poloxamer 403.
Frequently Asked Questions
Is Poloxamer 403 allowed in the EU?
Poloxamer 403 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamer 403 do in cosmetics?
Poloxamer 403 functions as: Surfactant – Cleansing; Surfactant – Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic for all Poloxamers).
Compliance Tools
Check Poloxamer 403 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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