Is Poloxamer 401 safe in cosmetics?
Poloxamer 401 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Poloxamer 401
INCI: POLOXAMER 401
Poloxamer 401 (CAS 9003-11-6 (generic)) is a cosmetic cosmetic ingredient functioning as Surfactant – cleansing, surfactant – emulsifying. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9003-11-6 (generic) →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant – cleansing, surfactant – emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: safe as used (2008); 2 reported uses in body/hand creams (Pluronic L-121)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Poloxamer 401.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Poloxamer 401.
Frequently Asked Questions
Is Poloxamer 401 allowed in the EU?
Poloxamer 401 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamer 401 do in cosmetics?
Poloxamer 401 functions as: Surfactant – cleansing, surfactant – emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic).
Compliance Tools
Check Poloxamer 401 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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