Is Poloxamer 251 safe in cosmetics?
Poloxamer 251 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Poloxamer 251
INCI: POLOXAMER 251
Poloxamer 251 (CAS 9003-11-6 (generic poloxamer CAS)) is a cosmetic cosmetic ingredient functioning as Surfactant, emulsifying agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9003-11-6 (generic poloxamer CAS) →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant, emulsifying agent
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not included in the CIR 2008 safety assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Poloxamer 251.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Poloxamer 251.
Frequently Asked Questions
Is Poloxamer 251 allowed in the EU?
Poloxamer 251 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Poloxamer 251 do in cosmetics?
Poloxamer 251 functions as: Surfactant, emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 9003-11-6 (generic poloxamer CAS).
Compliance Tools
Check Poloxamer 251 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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