Good Cosmetic Ingredient NOAEL Data

Pigment Red 90:1 Aluminum Lake

INCI: PIGMENT RED 90:1 ALUMINUM LAKE

Pigment Red 90:1 Aluminum Lake (CAS 15876-39-8) is a cosmetic cosmetic ingredient functioning as Colorant. Reported NOAEL =500 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 15876-39-8 →

Auto-generated CPSR Part A draft with source citations
Function
Colorant
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
240-005-7

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes D&C Red No. 22 lake — permanently listed, certification required; permitted in lipsticks and externally applied cosmetics; not permitted for eye area

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Pigment Red 90:1 Aluminum Lake.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Pigment Red 90:1 Aluminum Lake. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =500 mg/kg bw/day oral Rat short-term ToxValDB_ECHA_IUCLID
NOAEL =1000 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Dye

Expert Verdict

Expert safety assessment and concern-level summary for Pigment Red 90:1 Aluminum Lake.

Regulatory Flags

colorant

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Pigment Red 90:1 Aluminum Lake by CAS number or substance name.

Studies
2
Lowest NOAEL
500 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Dye

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Pigment Red 90:1 Aluminum Lake safe in cosmetics?

Pigment Red 90:1 Aluminum Lake has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.

Is Pigment Red 90:1 Aluminum Lake allowed in the EU?

Pigment Red 90:1 Aluminum Lake EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pigment Red 90:1 Aluminum Lake do in cosmetics?

Pigment Red 90:1 Aluminum Lake functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 15876-39-8.

What is the NOAEL for Pigment Red 90:1 Aluminum Lake?

The NOAEL (No Observed Adverse Effect Level) for Pigment Red 90:1 Aluminum Lake is =500 mg/kg bw/day based on a short-term study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is Pigment Red 90:1 Aluminum Lake used outside cosmetics?

Pigment Red 90:1 Aluminum Lake also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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