Is Piceatannol safe in cosmetics?
Piceatannol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Piceatannol
Also known as: NSC 365798, NSC 622471, 3,5,3',4'-tetrahydroxystilbene, 3-hydroxyresveratol, 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol
INCI: PICEATANNOL
Piceatannol (CAS 10083-24-6) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Conditioning (stilbenoid; resveratrol analogue). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 10083-24-6 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Conditioning (stilbenoid; resveratrol analogue)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
InChIKey
CDRPUGZCRXZLFL-OWOJBTEDSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted under general cosmetic provisions; also used in dietary supplements
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Piceatannol.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
anti_pollution
{"cas_number": "10083-24-6", "ingredient_class": "Nrf2_activator", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF…
uv_stability
{"uv_stable": "partially", "uv_degradation_rate": "moderate", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "yes", "color_change_uv": "yes", "odor_change_uv": "no", "efficacy_loss_uv_pct": "35", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for Piceatannol.
Known Synonyms
NSC 365798
NSC 622471
3,5,3',4'-tetrahydroxystilbene
3-hydroxyresveratol
4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol
Chemical Function
Antioxidant
Regulatory Lists
Canada; pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
PICEATANNOL
ChEMBL ID
CHEMBL69863
Frequently Asked Questions
Is Piceatannol allowed in the EU?
Piceatannol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Piceatannol do in cosmetics?
Piceatannol functions as: Antioxidant, Skin Conditioning (stilbenoid; resveratrol analogue). It is classified as a cosmetic ingredient in our database. CAS number: 10083-24-6.
Is Piceatannol used outside cosmetics?
Piceatannol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Piceatannol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Not Reported
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