Is Phosphatidylinositol safe in cosmetics?
Phosphatidylinositol has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Phosphatidylinositol
INCI: PHOSPHATIDYLINOSITOL
Phosphatidylinositol (CAS 383907-36-6 (sodium salt)) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin conditioning, surfactant, emulsifying agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 383907-36-6 (sodium salt) →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, skin conditioning, surfactant, emulsifying agent
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel (2020): safe in present practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phosphatidylinositol.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "barrier-repair", "mechanism_of_action": "Lipid barrier restoration, TEWL reduction, emollient", "target_skin_layer": "stratum corneum", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Int J Cosmet Sci, P…
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.25-0.38", "emulsion_stabilization_mechanism": "electrostatic_steric", "co_emulsifier_pairs": "xanthan_gum", "optimal_oil_phase_pct": "10-30", "optimal_water_phase_pct": "70-90", "electrolyte_tolerance": "low", "pH_emulsion_stability_range": "4.5-8.0", "viscosity_building_contribution": "low-moderate", …
Expert Verdict
Expert safety assessment and concern-level summary for Phosphatidylinositol.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Phosphatidylinositol allowed in the EU?
Phosphatidylinositol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phosphatidylinositol do in cosmetics?
Phosphatidylinositol functions as: Antioxidant, skin conditioning, surfactant, emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 383907-36-6 (sodium salt).
Compliance Tools
Check Phosphatidylinositol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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