Is Phenylalanine safe in cosmetics?
Phenylalanine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Phenylalanine
INCI: PHENYLALANINE
Phenylalanine (CAS 63-91-2 (L-Phenylalanine)) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-static. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 63-91-2 (L-Phenylalanine) →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-static
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; essential amino acid, GRAS status
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Phenylalanine.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
3 property records from structured ingredient metadata.
acne
{"cas_number": "63-91-2", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_ac…
anti_aging
{"anti_aging_claim": "barrier-repair", "mechanism_of_action": "Building block for proteins, NMF component", "target_skin_layer": "epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "4-8", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Int J Cosmet Sci", "improvement_…
sensory
{"silky": "powdery", "smooth, glides easily": "smooth, precursor", "dry-touch, non-greasy": "balanced, smooth", "instant": "moderate", "low": "low", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.28", "transparent": "opaque", "colorless": "white", "excellent": "fair", "light": "light", "synthetic": "biotechnology"}
Expert Verdict
Expert safety assessment and concern-level summary for Phenylalanine.
Frequently Asked Questions
Is Phenylalanine allowed in the EU?
Phenylalanine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Phenylalanine do in cosmetics?
Phenylalanine functions as: Skin conditioning, anti-static. It is classified as a cosmetic ingredient in our database. CAS number: 63-91-2 (L-Phenylalanine).
Compliance Tools
Check Phenylalanine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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