Is Pentaerythrityl Tetrabenzoate safe in cosmetics?
Pentaerythrityl Tetrabenzoate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Pentaerythrityl Tetrabenzoate
Also known as: 1,3-Propanediol, 2,2-bis[(benzoyloxy)methyl]-, 1,3-dibenzoate, Benzoflex S 552, 1,3-Propanediol, 2,2-bis[(benzoyloxy)methyl]-, dibenzoate, NSC 166502, Pentaerythritol, tetrabenzoate (+10 more)
INCI: PENTAERYTHRITYL TETRABENZOATE
Pentaerythrityl Tetrabenzoate (CAS 4196-86-5) is a cosmetic cosmetic ingredient functioning as Binder, skin-conditioning agent (emollient), viscosity-increasing agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 4196-86-5 →
Auto-generated CPSR Part A draft with source citations
Function
Binder, skin-conditioning agent (emollient), viscosity-increasing agent (nonaqueous)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[3-benzoyloxy-2,2-bis(benzoyloxymethyl)propyl] benzoate
InChIKey
MINJAOUGXYRTEI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel: safe in present practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Pentaerythrityl Tetrabenzoate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Pentaerythrityl Tetrabenzoate.
Known Synonyms
1,3-Propanediol, 2,2-bis[(benzoyloxy)methyl]-, 1,3-dibenzoate
Benzoflex S 552
1,3-Propanediol, 2,2-bis[(benzoyloxy)methyl]-, dibenzoate
NSC 166502
Pentaerythritol, tetrabenzoate
Pentaerythritol tetrabenzoate homopolymer
[3-Benzoyloxy-2,2-bis(benzoyloxymethyl)propyl] benzoate
pentaerythritol tetrabenzoate
DIBENZOATE, 2,2-BIS[(BENZYLOXY)METHYL]-1,3- PROPENEDIYL
EC No.: 224-079-8
2,2-Bis[(benzoyloxy)methyl]dibenzoate propanediol
2,2-Bis((benzoyloxy)methyl)dibenzoate propanediol
BRN 3513249
EINECS 224-079-8
UNII-U7L44GIS4O
Chemical Function
Softener and conditioner
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1533629
Frequently Asked Questions
Is Pentaerythrityl Tetrabenzoate allowed in the EU?
Pentaerythrityl Tetrabenzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pentaerythrityl Tetrabenzoate do in cosmetics?
Pentaerythrityl Tetrabenzoate functions as: Binder, skin-conditioning agent (emollient), viscosity-increasing agent (nonaqueous). It is classified as a cosmetic ingredient in our database. CAS number: 4196-86-5.
Is Pentaerythrityl Tetrabenzoate used outside cosmetics?
Pentaerythrityl Tetrabenzoate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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