Is PEG-8 Caprylic/Capric Glycerides safe in cosmetics?
PEG-8 Caprylic/Capric Glycerides has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
PEG-8 Caprylic/Capric Glycerides
Also known as: EC 287-488-0, Glycerides, C8-10 mono- and di-, C8-10 mixed mono- and diglycerides
INCI: PEG-8 CAPRYLIC/CAPRIC GLYCERIDES
PEG-8 Caprylic/Capric Glycerides (CAS 85536-07-8) is a cosmetic cosmetic ingredient functioning as Emulsifier. NOAEL 2390 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 85536-07-8 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifier
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3,12-bis[5-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)penta-1,3-dienyl]-4,13-dioxo-1,5,10,14-tetraoxadispiro[5.2.59.26]hexadeca-2,11-diene-2,11-diolate;3,12-bis[5-(2,4-dioxo-1,5-dioxaspiro[5.5]undecan-3-ylidene)penta-1,3-dienyl]-4,13-dioxo-1,5,10,14-tetraoxadispiro[5.2.59.26]hexadeca-2,11-diene-2,11-diolate;3-[5-[12-[5-(8,11-dimethyl-2-oxido-4-oxo-1,5-dioxaspiro[5.5]undec-2-en-3-yl)penta-2,4-dienylidene]-2,4,11,13-tetraoxo-1,5,10,14-tetraoxadispiro[5.2.59.26]hexadecan-3-ylidene]penta-1,3-dienyl]-8,11-dimethyl-4-oxo-1,5-dioxaspiro[5.5]undec-2-en-2-olate;2-ethyl-5-[5-[12-[5-(2-ethyl-2-methyl-4-oxido-6-oxo-1,3-dioxin-5-yl)penta-2,4-dienylidene]-2,4,11,13-tetraoxo-1,5,10,14-tetraoxadispiro[5.2.59.26]hexadecan-3-ylidene]penta-1,3-dienyl]-2-methyl-6-oxo-1,3-dioxin-4-olate;tetrakis(4-[4-[1-(4-hydroxy-3-phenylphenyl)pyridin-1-ium-4-yl]pyridin-1-ium-1-yl]-2-phenylphenol)
InChIKey
DENDBKLJAQIVGF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR assessed PEGylated alkyl glycerides as safe; oral LD50 in rats 22 g/kg indicating very low acute toxicity; also a pharmaceutical excipient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PEG-8 Caprylic/Capric Glycerides.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for PEG-8 Caprylic/Capric Glycerides across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
surfactant
{"cas_number": "45928-63-3", "surfactant_type": "nonionic", "chemical_class": "ethoxylate", "charge_at_use_ph": "neutral", "cmc_critical_micelle_concentration_mm": "0.02687129790990766", "hlb_value": "9.824211552793411", "foam_volume_ml_ross_miles": "104", "foam_quality": "airy", "foam_stability_5min_pct": "59", "cleansing_power_rating_1_to_10": "4.56237826629817", "oil_emulsification_capacity": "…
Expert Verdict
Expert safety assessment and concern-level summary for PEG-8 Caprylic/Capric Glycerides.
Regulatory Flags
peg-ingredient
ethoxylated
Known Synonyms
EC 287-488-0
Glycerides, C8-10 mono- and di-
C8-10 mixed mono- and diglycerides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-8 Caprylic/Capric Glycerides allowed in the EU?
PEG-8 Caprylic/Capric Glycerides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-8 Caprylic/Capric Glycerides do in cosmetics?
PEG-8 Caprylic/Capric Glycerides functions as: Emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: 85536-07-8.
Is PEG-8 Caprylic/Capric Glycerides used outside cosmetics?
PEG-8 Caprylic/Capric Glycerides also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check PEG-8 Caprylic/Capric Glycerides compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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