Is PEG-25 CASTOR OIL safe in cosmetics?
PEG-25 CASTOR OIL has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 2 toxicological study endpoint(s) are available in our database.
PEG-25 CASTOR OIL
Also known as: Castor oil, ethoxylated, Cremophor EL Castor Oil, POLYOXYETHYLENE CASTOR ETHE, OILS, POLYOXY ETHYLATED CASTOR, OILS, CASTOR, ETHOXYLATED (+15 more)
PEG-25 CASTOR OIL (CAS 61791-12-6) is a cosmetic cosmetic ingredient functioning as Surfactant - Cleansing, Surfactant - Emulsifying. Reported NOAEL =46.25 mg/kg bw/day in Dog (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 61791-12-6 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant - Cleansing, Surfactant - Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR: SQ - IJT 33(Suppl 4):13-39, 2014
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for PEG-25 CASTOR OIL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =46.25 mg/kg bw/day | oral | Dog | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =480 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Dispersing agent
Emulsifier
Fragrance
Lubricating agent
Processing aids not otherwise specified
Softener and conditioner
Surface modifier
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for PEG-25 CASTOR OIL.
Regulatory Flags
cosing-sourced
eu-permitted
surfactant
needs-enrichment
epa_safer_alternative
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-25 CASTOR OIL by CAS number or substance name.
Studies
2
Lowest NOAEL
46.25 mg/kg bw/day
Highest NOAEL
480 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Castor oil, ethoxylated
Cremophor EL Castor Oil
POLYOXYETHYLENE CASTOR ETHE
OILS, POLYOXY ETHYLATED CASTOR
OILS, CASTOR, ETHOXYLATED
Caster oil ethoxylated
PEG 200 castor oil
PEG 75 castor oil
EC No.: 500-151-7
Cremaphor
Emulphor EL-620
Polyoxyethylated castor oil
UNII-6D4M1DAL6O
Polyoxyl 35 castor oil
UNII-4ERD2076EF
UNII-GF873K38RZ
UNII-VXP26NM2XX
Castor oil, ethoxylated (36 mol EO average molar ratio)
Polyethylene glycol (36) castor oil
Polyoxyethylene (36) castor oil
Chemical Function
Cleaning agent
Surfactant (surface active agent)
Regulatory Lists
SCIL (9/2019)
Indirect additives food contact (10/2018)
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
consumer_product
fracking; water
consumer_product
Indirect additives food contact (10/2018)
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-25 CASTOR OIL allowed in the EU?
PEG-25 CASTOR OIL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-25 CASTOR OIL do in cosmetics?
PEG-25 CASTOR OIL functions as: Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 61791-12-6.
What is the NOAEL for PEG-25 CASTOR OIL?
The NOAEL (No Observed Adverse Effect Level) for PEG-25 CASTOR OIL is =46.25 mg/kg bw/day based on a subchronic study via oral route in Dog. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is PEG-25 CASTOR OIL used outside cosmetics?
PEG-25 CASTOR OIL also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check PEG-25 CASTOR OIL compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Alpha-Glucan Oligosaccharide-1
Excellent
Same category
Skin conditioning, cleansing, smoothi...
Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer
Excellent
Same category
Dispersing agent (nonsurfactant), vis...
Ammonium Cocoyl Isethionate
Excellent
Same category
Surfactant – cleansing, foaming
Ammonium Lauryl Sulfosuccinate
Excellent
Same category
Cleansing, foaming, surfactant
Ammonium Stearate
Excellent
Same category
Cleansing, surfactant, emulsifying
Apricot Kernel Oil Polyglyceryl-10 Esters
Excellent
Same category
Skin conditioning, emollient, surfact...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
Castor Oil Hydrogenated Ethoxylated
Moderate
Chemical family
Surfactant – Emulsifying, Surfactant ...
Coceth-10
Good
Chemical family
Surfactant – emulsifying; surfactant ...
Coceth-20
Good
Chemical family
Emulsifying; surfactant
Is PEG-25 CASTOR OIL in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PEG-25 CASTOR OIL in your formulation.