Is PEG-200 Castor Oil safe in cosmetics?
PEG-200 Castor Oil has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
PEG-200 Castor Oil
Also known as: Castor oil, ethoxylated, Cremophor EL Castor Oil, POLYOXYETHYLENE CASTOR ETHE, OILS, POLYOXY ETHYLATED CASTOR, OILS, CASTOR, ETHOXYLATED (+15 more)
PEG-200 Castor Oil (CAS 61791-12-6) is a cosmetic cosmetic ingredient functioning as Cleaning agent; Dispersing agent; Emulsifier; Fragrance; Lubricating agent;. Reported NOAEL =46.25 mg/kg bw/day in Dog (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 61791-12-6 →
Auto-generated CPSR Part A draft with source citations
Function
Cleaning agent; Dispersing agent; Emulsifier; Fragrance; Lubricating agent; Processing aids not otherwise specified; Softener and conditioner; Surface modifier; Surfactant (surface active agent); Wetting agent (non-aqueous)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR: SQ - IJT 33(Suppl 4):13-39, 2014
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for PEG-200 Castor Oil.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for PEG-200 Castor Oil. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =46.25 mg/kg bw/day | oral | Dog | subchronic | ToxValDB_ECHA_IUCLID |
| NOAEL | =480 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsifier
{"cas_number": "61791-12-6", "ingredient_class": "O/W_emulsifier", "chemical_type": "PEG_ester", "HLB_value": "18.5", "HLB_required_for_oil_phase": "16-20", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "critical_micelle_concentration_pct": "0.005-0.02", "surface_tension_reduction_mN_m": "64", "interfacial_tension_reduction": "68", "foam_formation": "moderate", "foam_stabilit…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Dispersing agent
Emulsifier
Fragrance
Lubricating agent
Processing aids not otherwise specified
Softener and conditioner
Surface modifier
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Indirect Food Contact Additives
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for PEG-200 Castor Oil.
Regulatory Flags
plant-oil
peg-ingredient
epa_safer_alternative
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-200 Castor Oil by CAS number or substance name.
Studies
2
Lowest NOAEL
46.25 mg/kg bw/day
Highest NOAEL
480 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Castor oil, ethoxylated
Cremophor EL Castor Oil
POLYOXYETHYLENE CASTOR ETHE
OILS, POLYOXY ETHYLATED CASTOR
OILS, CASTOR, ETHOXYLATED
Caster oil ethoxylated
PEG 200 castor oil
PEG 75 castor oil
EC No.: 500-151-7
Cremaphor
Emulphor EL-620
Polyoxyethylated castor oil
UNII-6D4M1DAL6O
Polyoxyl 35 castor oil
UNII-4ERD2076EF
UNII-GF873K38RZ
UNII-VXP26NM2XX
Castor oil, ethoxylated (36 mol EO average molar ratio)
Polyethylene glycol (36) castor oil
Polyoxyethylene (36) castor oil
Chemical Function
Cleaning agent
Surfactant (surface active agent)
Regulatory Lists
SCIL (9/2019)
Indirect additives food contact (10/2018)
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
IFRA Transparency
consumer_product
fracking; water
consumer_product
Indirect additives food contact (10/2018)
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-200 Castor Oil allowed in the EU?
PEG-200 Castor Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-200 Castor Oil do in cosmetics?
PEG-200 Castor Oil functions as: Cleaning agent; Dispersing agent; Emulsifier; Fragrance; Lubricating agent; Processing aids not otherwise specified; Softener and conditioner; Surface modifier; Surfactant (surface active agent); Wetting agent (non-aqueous). It is classified as a cosmetic ingredient in our database. CAS number: 61791-12-6.
What is the NOAEL for PEG-200 Castor Oil?
The NOAEL (No Observed Adverse Effect Level) for PEG-200 Castor Oil is =46.25 mg/kg bw/day based on a subchronic study via oral route in Dog. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is PEG-200 Castor Oil used outside cosmetics?
PEG-200 Castor Oil also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check PEG-200 Castor Oil compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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