Is PEG-20 COCAMINE safe in cosmetics?
PEG-20 COCAMINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 10 toxicological study endpoint(s) are available in our database.
PEG-20 COCAMINE
Also known as: PEG-4 cocamine, Ethoxylated cocoamines, UNII-28053HD34J, UNII-2F9J4Q575K, UNII-8L6LB12TSJ (+4 more)
PEG-20 COCAMINE (CAS 61791-14-8) is a cosmetic cosmetic ingredient functioning as Surfactant - Cleansing, Surfactant - Emulsifying. Reported NOAEL =5 mg/kg/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 61791-14-8 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant - Cleansing, Surfactant - Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR: SQ - IJT 39(S2):26-58,2020
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
10 study endpoints found for PEG-20 COCAMINE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =5 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =5 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =5 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =5 mg/kg/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =12 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =12 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =12 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =12 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =13 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =13 mg/kg/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Cleaning agent
Dispersing agent
Emulsifier
Surface modifier
Surfactant (surface active agent)
Thickening agent
Wetting agent (non-aqueous)
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for PEG-20 COCAMINE.
Regulatory Flags
cosing-sourced
eu-permitted
surfactant
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-20 COCAMINE by CAS number or substance name.
Studies
48
Lowest NOAEL
5 mg/kg/d
Highest NOAEL
134 mg/kg/d
CIR_vision_codex
Known Synonyms
PEG-4 cocamine
Ethoxylated cocoamines
UNII-28053HD34J
UNII-2F9J4Q575K
UNII-8L6LB12TSJ
UNII-KTM00873VC
UNII-PMT39AFQ4Z
UNII-Z99UKQ29D9
UNII-ZA36V5XS8F
Chemical Function
Surfactant (surface active agent)
Emulsifier
Cleaning agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Indirect additives food contact (10/2018)
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care - hair styling and care - shampoo-dandruff
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-20 COCAMINE allowed in the EU?
PEG-20 COCAMINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-20 COCAMINE do in cosmetics?
PEG-20 COCAMINE functions as: Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 61791-14-8.
What is the NOAEL for PEG-20 COCAMINE?
The NOAEL (No Observed Adverse Effect Level) for PEG-20 COCAMINE is =5 mg/kg/d based on a developmental toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.
Compliance Tools
Check PEG-20 COCAMINE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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