Is PEG-100 HYDROGENATED CASTOR OIL safe in cosmetics?
PEG-100 HYDROGENATED CASTOR OIL has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted. 2 toxicological study endpoint(s) are available in our database.
PEG-100 HYDROGENATED CASTOR OIL
Also known as: HCO 40, HCO 50, Castor oil, hydrogenated, ethoxylated, Cremophor RH 40, Polyoxyethylene hydrogenated castor oil 60 (+13 more)
PEG-100 HYDROGENATED CASTOR OIL (CAS 61788-85-0) is a cosmetic cosmetic ingredient functioning as Surfactant - Cleansing, Surfactant - Emulsifying. NOAEL 1250 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 61788-85-0 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant - Cleansing, Surfactant - Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR: SQ - IJT 33(Suppl 4):13-39, 2014
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for PEG-100 HYDROGENATED CASTOR OIL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Mouse | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =5000 mg/kg bw/day | oral | Mouse | reproduction developmental | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for PEG-100 HYDROGENATED CASTOR OIL across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsifier
{"cas_number": "61788-85-0", "ingredient_class": "O/W_emulsifier", "chemical_type": "PEG_ester", "HLB_value": "14.4", "HLB_required_for_oil_phase": "12-16", "emulsion_type_primary": "O/W", "droplet_size_typical_um": "0.5-2", "critical_micelle_concentration_pct": "0.005-0.02", "surface_tension_reduction_mN_m": "44", "interfacial_tension_reduction": "48", "foam_formation": "moderate", "foam_stabilit…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Fragrance
Lubricating agent
Softener and conditioner
Solubility enhancer
Solvent
Surfactant (surface active agent)
Regulatory List Membership (3)
EU Restricted for Children (Cosmetics)
IFRA Fragrance Transparency List
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for PEG-100 HYDROGENATED CASTOR OIL.
Regulatory Flags
cosing-sourced
eu-permitted
surfactant
needs-enrichment
eu_children_restricted
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to PEG-100 HYDROGENATED CASTOR OIL by CAS number or substance name.
Studies
2
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
5000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
HCO 40
HCO 50
Castor oil, hydrogenated, ethoxylated
Cremophor RH 40
Polyoxyethylene hydrogenated castor oil 60
EC No.: 500-147-5
EC No.: 613-097-5
EC No.: 918-326-5
UNII-7YC686GQ8F
UNII-02NG325BQG
UNII-0ZNO9PJJ9J
UNII-R07D3A9614
UNII-0WZF1506N9
UNII-MH590ECD4O
UNII-WE09129TH5
UNII-43SW2U113W
Polyoxyl 40 hydrogenated castor oil
PEG-50 Hydrogenated Castor Oil
Chemical Function
Surfactant (surface active agent)
Emulsifier
Regulatory Lists
Indirect additives food contact (10/2018)
IFRA Transparency
inert_ingredient; non_food_use; Pesticides
Europe; Personal care - body hygiene - hand soap
children; Europe; Personal care
children; Europe; Personal care
children; Europe; Personal care - body hygiene - body wash
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PEG-100 HYDROGENATED CASTOR OIL allowed in the EU?
PEG-100 HYDROGENATED CASTOR OIL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PEG-100 HYDROGENATED CASTOR OIL do in cosmetics?
PEG-100 HYDROGENATED CASTOR OIL functions as: Surfactant - Cleansing, Surfactant - Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 61788-85-0.
What is the NOAEL for PEG-100 HYDROGENATED CASTOR OIL?
The NOAEL (No Observed Adverse Effect Level) for PEG-100 HYDROGENATED CASTOR OIL is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Mouse. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Compliance Tools
Check PEG-100 HYDROGENATED CASTOR OIL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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