Is PANTHENYL ETHYL ETHER safe in cosmetics?
PANTHENYL ETHYL ETHER has a safety rating of "GOOD" in our database. EU status: permitted. US status: prohibited.
Good
Cosmetic Ingredient
PANTHENYL ETHYL ETHER
Also known as: Butanamide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, (2R)-, Butanamide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, (R)-, Butyramide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, D-(+)-, (2R)-N-(3-Ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide, (+)-Pantothenyl ethyl ether (+8 more)
PANTHENYL ETHYL ETHER (CAS 667-83-4) is a cosmetic cosmetic ingredient functioning as Antistatic, Hair Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 667-83-4 →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Hair Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2R)-N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide
InChIKey
MRAMPOPITCOOIN-VIFPVBQESA-N
Regulatory Status
EU EU Status
permitted
US US Status
prohibited
US Notes
Allowed — not prohibited or restricted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
vitamin
{"cas_number": "667-83-4", "ingredient_class": "vitamin_B5", "chemical_form": "ether", "derivative_type": "stabilized", "molecular_weight_Da": "233.31", "water_solubility": "slightly", "oil_solubility": "soluble", "log_P": "0.20", "stability_to_light": "excellent", "stability_to_heat": "excellent", "stability_to_oxidation": "excellent", "stability_to_pH_acid": "excellent", "stability_to_pH_alkalin…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Softener and conditioner
Regulatory List Membership (1)
EU Regulated in Personal Care
Expert Verdict
Expert safety assessment and concern-level summary for PANTHENYL ETHYL ETHER.
Regulatory Flags
cosing-sourced
eu-permitted
hair-conditioning
needs-enrichment
Known Synonyms
Butanamide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, (2R)-
Butanamide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, (R)-
Butyramide, N-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethyl-, D-(+)-
(2R)-N-(3-Ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide
(+)-Pantothenyl ethyl ether
D-Pantothenyl ethyl ether
Ethyl panthenol
Pantyl
Provitamin B3
D-O-3'-ethylpantothenyl alcohol
dexpanthenol ethyl
O-3'-ethyldexpanthenol
EINECS No.: 211-569-1
Chemical Function
Anti-static agent
Softener and conditioner
Regulatory Lists
Europe; Personal care
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is PANTHENYL ETHYL ETHER allowed in the EU?
PANTHENYL ETHYL ETHER EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does PANTHENYL ETHYL ETHER do in cosmetics?
PANTHENYL ETHYL ETHER functions as: Antistatic, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 667-83-4.
Is PANTHENYL ETHYL ETHER used outside cosmetics?
PANTHENYL ETHYL ETHER also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check PANTHENYL ETHYL ETHER compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
ACETYL TRIPEPTIDE-45 D-PHENYLALANYL OCTAPEPTIDE-14 NORLEUCYL PENTAPEPTIDE-38 METHYL LEUCYL DECAPEPTIDE-26 NORLEUCYL GLUTAMYL METHYL LEUCYL ISOLEUCINAMIDE
Good
Same category
Hair Conditioning
AVENA SATIVA FLOWER/LEAF/STEM EXTRACT
Good
Same category
Hair Conditioning
BABASSUAMIDOPROPALKONIUM CHLORIDE
Good
Same category
Antistatic, Hair Conditioning
BEHENYL HYDROXYETHYL IMIDAZOLINE
Good
Same category
Antistatic, Hair Conditioning
BIS-CETEARAMIDOETHYLDIETHONIUM SUCCINOYL HYDROLYZED KERATIN
Good
Same category
Hair Conditioning
BIS-DIMONIUM METHOSULFATE
Good
Same category
Emulsion Stabilising, Hair Conditioning
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
PANAX GINSENG CALLUS/ADVENTITIOUS ROOT CELL
Good
Browse nearby
Hair Conditioning, Skin Conditioning
PANAX GINSENG CELL CULTURE EXTRACT
Good
Browse nearby
Skin Conditioning
PANAX GINSENG EXTRACT
Good
Browse nearby
Antioxidant, Oral Care, Skin Conditio...
Is PANTHENYL ETHYL ETHER in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PANTHENYL ETHYL ETHER in your formulation.