Is Oligopeptide-174 sh-Pentapeptide-4 sp safe in cosmetics?
Oligopeptide-174 sh-Pentapeptide-4 sp has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Oligopeptide-174 sh-Pentapeptide-4 sp
INCI: OLIGOPEPTIDE-174 / SH-PENTAPEPTIDE-4
Oligopeptide-174 sh-Pentapeptide-4 sp (CAS Not publicly assigned as a complex; sh-Pentapeptide-4 (synthetic human recombinant variant of Pentapeptide-4) is a separate CosIng entry. Pentapeptide-4 base CAS: 149128-48-3 [^1_8]; Palmitoyl Pentapeptide-4 CAS: 214047-00-4 [^1_9]) is a cosmetic cosmetic ingredient functioning as Skin conditioning, antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly assigned as a complex; sh-Pentapeptide-4 (synthetic human recombinant variant of Pentapeptide-4) is a separate CosIng entry. Pentapeptide-4 base CAS: 149128-48-3 [^1_8]; Palmitoyl Pentapeptide-4 CAS: 214047-00-4 [^1_9]
View industrial chemical safety profile →
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Pentapeptide-4 derivatives have CIR review (safe as used); the sh- recombinant variant and blend not independently reviewed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Oligopeptide-174 sh-Pentapeptide-4 sp.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Oligopeptide-174 sh-Pentapeptide-4 sp.
Frequently Asked Questions
Is Oligopeptide-174 sh-Pentapeptide-4 sp allowed in the EU?
Oligopeptide-174 sh-Pentapeptide-4 sp EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Oligopeptide-174 sh-Pentapeptide-4 sp do in cosmetics?
Oligopeptide-174 sh-Pentapeptide-4 sp functions as: Skin conditioning, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned as a complex; sh-Pentapeptide-4 (synthetic human recombinant variant of Pentapeptide-4) is a separate CosIng entry. Pentapeptide-4 base CAS: 149128-48-3 [^1_8]; Palmitoyl Pentapeptide-4 CAS: 214047-00-4 [^1_9].
Compliance Tools
Check Oligopeptide-174 sh-Pentapeptide-4 sp compliance across multiple jurisdictions:
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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