Is Oleuropein safe in cosmetics?
Oleuropein has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Antioxidant
Oleuropein
Also known as: 2-(3,4-Dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate
INCI: OLEUROPEIN
Oleuropein (CAS 32619-42-4) is a cosmetic antioxidant functioning as Antioxidant, Hair Conditioning, Anti-Inflammatory. EU Regulation 1223/2009 status: permitted, max 2%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 32619-42-4 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Hair Conditioning, Anti-Inflammatory
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
InChIKey
RFWGABANNQMHMZ-ZCHJGGQASA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
2%
US US Status
permitted
US Notes
CIR Panel concluded 16 olive-derived ingredients (including Olea Europaea Leaf Extract) safe in cosmetics in present practices of use (September 2023). FEMA GRAS as flavor ingredient (120 ppm avg, 720 ppm max).
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Oleuropein.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Hair fixative
Hair waving or straightening
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Oleuropein.
Known Synonyms
2-(3,4-Dihydroxyphenyl)ethyl (2S-(2alpha,3E,4beta))-3-ethylidene-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetate
Chemical Function
Antioxidant
Softener and conditioner
Hair fixative
Hair waving or straightening
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
OLEUROPEIN
ChEMBL ID
CHEMBL1911053
Frequently Asked Questions
Is Oleuropein allowed in the EU?
Oleuropein EU regulatory status: permitted. Maximum allowed concentration: 2%. This is based on EU Regulation 1223/2009 and its amendments.
What does Oleuropein do in cosmetics?
Oleuropein functions as: Antioxidant, Hair Conditioning, Anti-Inflammatory. It is classified as a Antioxidant in our database. CAS number: 32619-42-4.
Is Oleuropein used outside cosmetics?
Oleuropein also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Oleuropein compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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OLEA EUROPAEA CALLUS CULTURE LYSATE
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