Is NONYL ACETATE safe in cosmetics?
NONYL ACETATE has a safety rating of "GOOD" in our database. EU status: permitted. US status: allowed.
Good
Cosmetic Ingredient
NONYL ACETATE
Also known as: Acetic acid, nonyl ester, Acetate C-9, Acetic acid n-nonyl ester, 1-Acetoxynonane, EINECS 205-585-8 (+11 more)
NONYL ACETATE (CAS 143-13-5) is a cosmetic cosmetic ingredient functioning as Perfuming, Skin Conditioning - Emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 143-13-5 →
Auto-generated CPSR Part A draft with source citations
Function
Perfuming, Skin Conditioning - Emollient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
nonyl acetate
InChIKey
GJQIMXVRFNLMTB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
allowed
US Notes
Allowed — no restrictions; also FEMA GRAS approved as a flavoring agent
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1296 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
131
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
NONYL ACETATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Softener and conditioner
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for NONYL ACETATE.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
emollient
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Acetic acid, nonyl ester
Acetate C-9
Acetic acid n-nonyl ester
1-Acetoxynonane
EINECS 205-585-8
FEMA No. 2788
Nonanol acetate
n-Nonanyl acetate
1-Nonyl acetate
Nonyl alcohol, acetate
Nonyl ethanoate
n-Nonyl ethanoate
NSC 82356
Pelargonyl acetate
UNII-M2SE618B1L
acetic acid nonyl ester
Chemical Function
Softener and conditioner
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NONYLACETATE
ChEMBL ID
CHEMBL2228457
Frequently Asked Questions
Is NONYL ACETATE allowed in the EU?
NONYL ACETATE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NONYL ACETATE do in cosmetics?
NONYL ACETATE functions as: Perfuming, Skin Conditioning - Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 143-13-5.
Is NONYL ACETATE used outside cosmetics?
NONYL ACETATE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check NONYL ACETATE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Chemical family
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Chemical family
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DEA-Lauryl Sulfate
Moderate
Chemical family
Surfactant - cleansing, foaming
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