Is Niranthin safe in cosmetics?
Niranthin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Niranthin
INCI: NIRANTHIN
Niranthin (CAS 50656-77-4) is a cosmetic cosmetic ingredient functioning as Antioxidant, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 50656-77-4 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
6-[(2S,3S)-3-[(3,4-dimethoxyphenyl)methyl]-4-methoxy-2-(methoxymethyl)butyl]-4-methoxy-1,3-benzodioxole
InChIKey
RCFGIEPQSDGMJJ-RTBURBONSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Lignan isolated from Phyllanthus niruri; primarily researched for anti-hepatitis B, anti-leishmanial, and anti-inflammatory activity; no established cosmetic INCI safety assessment; suppliers label as research-use only.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Niranthin.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Niranthin.
Regulatory Flags
phytochemical
lignan
research-compound
no-inci-assessment
investigational
Frequently Asked Questions
Is Niranthin allowed in the EU?
Niranthin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Niranthin do in cosmetics?
Niranthin functions as: Antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 50656-77-4.
Compliance Tools
Check Niranthin compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
NISIN
Good
Browse nearby
Antimicrobial
NITRILES COCO
Good
Browse nearby
Perfuming
NITROCELLULOSE
Good
Browse nearby
Film-forming agent; nail lacquer prim...
NITROETHANE
Good
Browse nearby
Solvent
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Same EU status
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Same EU status
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Same EU status
Is Niranthin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Niranthin in your formulation.