Is Nicotinyl Alcohol safe in cosmetics?
Nicotinyl Alcohol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Nicotinyl Alcohol
Also known as: 5-21-02-00172, BRN 0107851, EINECS 202-864-6, beta-Picolyl alcohol, 3-Picolyl alcohol (+2 more)
INCI: NICOTINYL ALCOHOL
Nicotinyl Alcohol (CAS 100-55-0) is a cosmetic cosmetic ingredient functioning as Skin Conditioning (vasodilator — stimulates local blood circulation). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 100-55-0 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning (vasodilator — stimulates local blood circulation)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
pyridin-3-ylmethanol
InChIKey
MVQVNTPHUGQQHK-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR. Note: also has pharmaceutical monograph (USAN)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Nicotinyl Alcohol.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Nicotinyl Alcohol.
Known Synonyms
5-21-02-00172
BRN 0107851
EINECS 202-864-6
beta-Picolyl alcohol
3-Picolyl alcohol
beta-Pyridinecarbinol
UNII-9TF312056Y
Chemical Function
Humectant
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NICOTINYL ALCOHOL
ChEMBL ID
CHEMBL1235535
Max Phase
-1
Frequently Asked Questions
Is Nicotinyl Alcohol allowed in the EU?
Nicotinyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Nicotinyl Alcohol do in cosmetics?
Nicotinyl Alcohol functions as: Skin Conditioning (vasodilator — stimulates local blood circulation). It is classified as a cosmetic ingredient in our database. CAS number: 100-55-0.
Is Nicotinyl Alcohol used outside cosmetics?
Nicotinyl Alcohol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Nicotinyl Alcohol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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