Is NEOSAXITOXIN safe in cosmetics?
NEOSAXITOXIN has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
NEOSAXITOXIN
Also known as: [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-5-oxido-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-5-ium-4-yl]methyl carbamate, 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-(((aminocarbonyl)oxy)methyl)-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS,4R,10aS)-, 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-((aminocarbonyl)oxy)methyl-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS,4R,10aS)-, 1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-((aminocarbonyl)oxy)methyl-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS-(3aalpha,4alpha,10aR*))-, NeoSTX
NEOSAXITOXIN (CAS 64296-20-4) is a cosmetic cosmetic ingredient functioning as Antioxidant, Antiperspirant, Astringent, Colorant, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 64296-20-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
NEOSAXITOXIN is classified GHS Danger (H300) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antioxidant, Antiperspirant, Astringent, Colorant, Skin Protecting
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(3aS,4R,10aS)-2-amino-5,10,10-trihydroxy-6-imino-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate
InChIKey
PPEKGEBBBBNZKS-HGRQIUPRSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Antiperspirant
Astringent
Dye
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for NEOSAXITOXIN.
Regulatory Flags
cosing-sourced
eu-permitted
antioxidant
needs-enrichment
Known Synonyms
[(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-5-oxido-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-5-ium-4-yl]methyl carbamate
1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-(((aminocarbonyl)oxy)methyl)-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS,4R,10aS)-
1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-((aminocarbonyl)oxy)methyl-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS,4R,10aS)-
1H,10H-Pyrrolo(1,2-c)purine-10,10-diol, 2-amino-4-((aminocarbonyl)oxy)methyl-3a,4,5,6,8,9-hexahydro-5-hydroxy-6-imino-, (3aS-(3aalpha,4alpha,10aR*))-
NeoSTX
Chemical Function
Antioxidant
Humectant
Astringent
Dye
Antiperspirant
Regulatory Lists
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
NEOSAXITOXIN
ChEMBL ID
CHEMBL4297307
Max Phase
1
Frequently Asked Questions
Is NEOSAXITOXIN allowed in the EU?
NEOSAXITOXIN EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does NEOSAXITOXIN do in cosmetics?
NEOSAXITOXIN functions as: Antioxidant, Antiperspirant, Astringent, Colorant, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 64296-20-4.
Is NEOSAXITOXIN used outside cosmetics?
NEOSAXITOXIN also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does NEOSAXITOXIN have different safety status in cosmetics vs industrial chemicals?
NEOSAXITOXIN is classified GHS Danger (H300) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check NEOSAXITOXIN compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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