Is Naringenin Chalcone safe in cosmetics?
Naringenin Chalcone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Naringenin Chalcone
INCI: NARINGENIN CHALCONE
Naringenin Chalcone (CAS 25515-46-2) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-redness, anti-inflammatory. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 25515-46-2 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-redness, anti-inflammatory
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(E)-3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
InChIKey
YQHMWTPYORBCMF-ZZXKWVIFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted by FDA; limited CIR-specific review; marketed as active cosmetic ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Naringenin Chalcone.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Naringenin Chalcone.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
4,2',4',6'-TETRAHYDROXYCHALCONE
ChEMBL ID
CHEMBL338066
Frequently Asked Questions
Is Naringenin Chalcone allowed in the EU?
Naringenin Chalcone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Naringenin Chalcone do in cosmetics?
Naringenin Chalcone functions as: Skin conditioning, anti-redness, anti-inflammatory. It is classified as a cosmetic ingredient in our database. CAS number: 25515-46-2.
Is Naringenin Chalcone used outside cosmetics?
Naringenin Chalcone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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