Is Methyl Xanthine safe in cosmetics?
Methyl Xanthine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Xanthine
Also known as: EINECS 209-019-0, NSC 7861, 1H-Purine-2,6-dione, 3,7-dihydro-7-methyl-, UNII-E9M81NJM6G, 2,6-Dihydroxy-7-methylpurine (+8 more)
INCI: METHYL XANTHINE (ALSO KNOWN AS 7-METHYLXANTHINE / HETEROXANTHINE)
Methyl Xanthine (CAS 552-62-5) is a cosmetic cosmetic ingredient functioning as Function not specifically reported in CosIng; closely related to caffeine,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 552-62-5 →
Auto-generated CPSR Part A draft with source citations
Function
Function not specifically reported in CosIng; closely related to caffeine, theobromine, and theophylline, which function as skin-conditioning agents
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
7-methyl-3H-purine-2,6-dione
InChIKey
PFWLFWPASULGAN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - CIR Expert Panel assessed the related methylxanthines (caffeine, theobromine, theophylline) as safe in current practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Xanthine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Xanthine.
Known Synonyms
EINECS 209-019-0
NSC 7861
1H-Purine-2,6-dione, 3,7-dihydro-7-methyl-
UNII-E9M81NJM6G
2,6-Dihydroxy-7-methylpurine
3,7-dihydro-7-methyl-1H-purine-2,6-dione
7-Methyl-3,7-dihydro-1H-purine-2,6-dione
7-Methyl-7H-purine-2,6-diol
7-Methylxanthin
7-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Heteroxanthin
Heteroxanthine
Methylxanthine
Chemical Function
No specific technical function
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
7-METHYLXANTHINE
ChEMBL ID
CHEMBL321248
Max Phase
2
Frequently Asked Questions
Is Methyl Xanthine allowed in the EU?
Methyl Xanthine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Xanthine do in cosmetics?
Methyl Xanthine functions as: Function not specifically reported in CosIng; closely related to caffeine, theobromine, and theophylline, which function as skin-conditioning agents. It is classified as a cosmetic ingredient in our database. CAS number: 552-62-5.
Is Methyl Xanthine used outside cosmetics?
Methyl Xanthine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methyl Xanthine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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