Is Methyl Perfluorobutyl Ether safe in cosmetics?
Methyl Perfluorobutyl Ether has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Perfluorobutyl Ether
Also known as: 1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane, 1-Methoxynonafluorobutane, Methoxyperfluorobutane, Methyl 1,1,2,2,3,3,4,4,4-nonafluorobutyl ether, Nonafluorobutyl methyl ether (+13 more)
INCI: METHYL PERFLUOROBUTYL ETHER
Methyl Perfluorobutyl Ether (CAS 163702-07-6) is a cosmetic cosmetic ingredient functioning as Solvent, Viscosity Controlling Agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 163702-07-6 →
Auto-generated CPSR Part A draft with source citations
Function
Solvent, Viscosity Controlling Agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxybutane
InChIKey
OKIYQFLILPKULA-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Explicitly listed by FDA as a common PFAS ingredient found in cosmetics. Allowed but under active assessment per MoCRA.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Perfluorobutyl Ether.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Solvent
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Perfluorobutyl Ether.
Known Synonyms
1,1,1,2,2,3,3,4,4-Nonafluoro-4-methoxybutane
1-Methoxynonafluorobutane
Methoxyperfluorobutane
Methyl 1,1,2,2,3,3,4,4,4-nonafluorobutyl ether
Nonafluorobutyl methyl ether
(Perfluorobutoxy)methane
methyl nonafluorobutyl ether
1-methoxy 1,1,2,2,3,3,4,4,4 nonafluorobutane
METHYL-(NONAFLUORBUTYL)-AETHER
1-Methoxy 1,1,2,2,3,3,4,4,4-nonafluorobutane
UNII-H637A50B7U
Cosmetic Fluid CF 61
HFC 7100
HFE 449mccc
Novec TM 7100
n 7100
HFE-7100
HFE-449s1 (HFE-7100) Chemical blend
Chemical Function
Solvent
Viscosity modifier
Regulatory Lists
consumer_product; Europe
Europe; Personal care - facial cleansing and moisturizing; Personal care - make-up and related
Europe; Personal care - facial cleansing and moisturizing; Personal care - make-up and related
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL500823
Frequently Asked Questions
Is Methyl Perfluorobutyl Ether allowed in the EU?
Methyl Perfluorobutyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Perfluorobutyl Ether do in cosmetics?
Methyl Perfluorobutyl Ether functions as: Solvent, Viscosity Controlling Agent. It is classified as a cosmetic ingredient in our database. CAS number: 163702-07-6.
Is Methyl Perfluorobutyl Ether used outside cosmetics?
Methyl Perfluorobutyl Ether also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methyl Perfluorobutyl Ether compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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