Is Methyl Aminolevulinate HCl safe in cosmetics?
Methyl Aminolevulinate HCl has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Aminolevulinate HCl
Also known as: EINECS 279-151-1, Metvix PDT, Metvixia, UNII-7S73606O1A, Methyl 5-aminolevulinate hydrochloride (+8 more)
INCI: METHYL AMINOLEVULINATE HCL
Methyl Aminolevulinate HCl (CAS 79416-27-6) is a cosmetic cosmetic ingredient functioning as Listed in CosIng as a cosmetic ingredient; however, its primary real-world use. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 79416-27-6 →
Auto-generated CPSR Part A draft with source citations
Function
Listed in CosIng as a cosmetic ingredient; however, its primary real-world use is pharmaceutical - as a photosensitizer in photodynamic therapy (PDT)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
methyl 5-amino-4-oxopentanoate;hydrochloride
InChIKey
UJYSYPVQHFNBML-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Approved as a prescription drug (NDA) for photodynamic therapy of actinic keratosis. Not a standard cosmetic ingredient in the US market
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Aminolevulinate HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Biocide
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Aminolevulinate HCl.
Known Synonyms
EINECS 279-151-1
Metvix PDT
Metvixia
UNII-7S73606O1A
Methyl 5-aminolevulinate hydrochloride
5-Aminolevulinic acid methyl ester hydrochloride
methyl 5-amino-4-oxopentanoate hydrochloride
methyl 5-amino-4-oxovalerate HCl
methyl 5-amino-4-oxovalerate hydrochloride
methyl 5-aminolevulinate HCl
methyl aminolevulinate hydrochloride
methyl delta-aminolevulinate HCl
methyl delta-aminolevulinate hydrochloride
Chemical Function
Biocide
Antioxidant
Humectant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
METHYL AMINOLEVULINATE HYDROCHLORIDE
ChEMBL ID
CHEMBL1201093
Max Phase
4
Frequently Asked Questions
Is Methyl Aminolevulinate HCl allowed in the EU?
Methyl Aminolevulinate HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Aminolevulinate HCl do in cosmetics?
Methyl Aminolevulinate HCl functions as: Listed in CosIng as a cosmetic ingredient; however, its primary real-world use is pharmaceutical - as a photosensitizer in photodynamic therapy (PDT). It is classified as a cosmetic ingredient in our database. CAS number: 79416-27-6.
Is Methyl Aminolevulinate HCl used outside cosmetics?
Methyl Aminolevulinate HCl also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Methyl Aminolevulinate HCl compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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