Is Methacryloyloxyethyl Isocyanate safe in cosmetics?
Methacryloyloxyethyl Isocyanate has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Methacryloyloxyethyl Isocyanate
Also known as: BRN 1768533, EINECS 250-284-7, beta-Isocyanatoethyl methacrylate, Isocyanoethyl methacrylate, Metharcyclic acid, 2-isocyanatoethyl ester (+1 more)
INCI: NOT ASSIGNED A COSMETIC INCI - NOT A COSMETIC INGREDIENT
Methacryloyloxyethyl Isocyanate (CAS 30674-80-7) is a cosmetic cosmetic ingredient functioning as Bifunctional reactive monomer (isocyanate + methacrylate) for industrial. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 30674-80-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Methacryloyloxyethyl Isocyanate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H330, H334, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Bifunctional reactive monomer (isocyanate + methacrylate) for industrial polymer crosslinking
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-isocyanatoethyl 2-methylprop-2-enoate
InChIKey
RBQRWNWVPQDTJJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Listed on EPA Consolidated List of Lists as an Extremely Hazardous Substance (EHS) with a threshold quantity of 100 lbs
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methacryloyloxyethyl Isocyanate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Skin Eye Respiratory Irritation
Isocyanates are irritating to the skin and the mucous membranes. Eye affections are less common and, although lacrimation is often found. /Isocyanates/
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chemical reaction regulator
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for Methacryloyloxyethyl Isocyanate.
Regulatory Flags
potential-allergen
Known Synonyms
BRN 1768533
EINECS 250-284-7
beta-Isocyanatoethyl methacrylate
Isocyanoethyl methacrylate
Metharcyclic acid, 2-isocyanatoethyl ester
UNII-828DBI7X91
Chemical Function
Chemical reaction regulator
No specific technical function
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Methacryloyloxyethyl Isocyanate allowed in the EU?
Methacryloyloxyethyl Isocyanate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Methacryloyloxyethyl Isocyanate do in cosmetics?
Methacryloyloxyethyl Isocyanate functions as: Bifunctional reactive monomer (isocyanate + methacrylate) for industrial polymer crosslinking. It is classified as a cosmetic ingredient in our database. CAS number: 30674-80-7.
Is Methacryloyloxyethyl Isocyanate used outside cosmetics?
Methacryloyloxyethyl Isocyanate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Methacryloyloxyethyl Isocyanate have different safety status in cosmetics vs industrial chemicals?
Methacryloyloxyethyl Isocyanate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H330, H334, H335).
Compliance Tools
Check Methacryloyloxyethyl Isocyanate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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