Is Metal Complexes Peptides safe in cosmetics?
Metal Complexes Peptides has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Metal Complexes Peptides
INCI: COPPER TRIPEPTIDE-1
Metal Complexes Peptides (CAS Category term — no single CAS; e.g., Copper Tripeptide-1 (GHK-Cu) = 89030-95-5) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-aging (collagen stimulation, wound healing support). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
Auto-generated CPSR Part A draft with source citations
CAS Number
Category term — no single CAS; e.g., Copper Tripeptide-1 (GHK-Cu) = 89030-95-5
View industrial chemical safety profile →
Function
Skin conditioning, anti-aging (collagen stimulation, wound healing support)
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR reviewed Tripeptide-1, Hexapeptide-12, their metal salts and fatty acyl derivatives — concluded safe as used in current practices and concentrations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Metal Complexes Peptides.
Calculate MoS for your specific formulation with the MoS Calculator.
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Serum | 0.001–0.05 | 0.1 | Industry |
Additional Ingredient Properties
10 property records from structured ingredient metadata.
amino_acid
{"cas_number": "49557-75-7", "ingredient_class": "tripeptide", "source_origin": "synthetic", "molecular_weight_range_Da": "340", "amino_acid_composition_key": "GHK_copper_complex", "charge_at_pH_5_5": "cationic", "water_solubility": "soluble", "oil_solubility": "insoluble", "film_forming_ability": "poor", "moisture_binding_capacity": "moderate", "NMF_component": "no", "skin_penetration_depth": "de…
anti_pollution
{"cas_number": "89030-95-5", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "free_radical_scavenging", "pollution_types_targeted": "PM2_5/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_mod…
baby_pediatric
{"cas_number": "49557-75-7/89030-95-5", "ingredient_class": "other", "pediatric_safety_rating": "avoid", "minimum_age_months": "24", "neonatal_safe": "no", "premature_infant_safe": "insufficient_data", "skin_barrier_maturity_consideration": "Copper peptide - adult", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "…
concentration
{"min_concentration_pct": "0.00001", "max_concentration_pct": "0.005", "typical_concentration_pct": "0.0005", "product_type": "Moisturizer", "function_at_concentration": "Skin repair", "source": "Clinical literature"}
ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "moderate", "coral_reef_safe": "unknown", "marine_toxicity": "copper toxicity concerns", "freshwater_toxicity": "metal accumulation", "endocrine_disruptor": "no", "persistent_organic_pollutant": "yes", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_e…
peptide
{"cas_number": "49557-75-7", "trade_name": "GHK-Cu / Copper Peptide", "peptide_sequence_amino_acids": "Gly-His-Lys-Cu2+", "peptide_length_residues": "3", "molecular_weight_daltons": "340.4", "peptide_class": "signal/carrier", "mechanism_of_action": "Copper delivery, wound healing, collagen/elastin stimulation, antioxidant, anti-inflammatory, MMP inhibition", "target_protein_or_receptor": "TGF-beta…
regulatory
{"eu_status": "allowed", "us_status": "allowed"}
self_tanning
{"cas_number": "49557-75-7", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "72.0", "full_color_development_hours": "240", "color_duration_days": "14", "color_depth": "light", "undertone": "natural", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release…
Expert Verdict
Expert safety assessment and concern-level summary for Metal Complexes Peptides.
Frequently Asked Questions
Is Metal Complexes Peptides allowed in the EU?
Metal Complexes Peptides EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Metal Complexes Peptides do in cosmetics?
Metal Complexes Peptides functions as: Skin conditioning, anti-aging (collagen stimulation, wound healing support). It is classified as a cosmetic ingredient in our database. CAS number: Category term — no single CAS; e.g., Copper Tripeptide-1 (GHK-Cu) = 89030-95-5.
Compliance Tools
Check Metal Complexes Peptides compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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