Is Menthyl Anthranilate safe in cosmetics?
Menthyl Anthranilate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Menthyl Anthranilate
Also known as: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate, EINECS 205-129-8, UNII-J9QGD60OUZ
INCI: MENTHYL ANTHRANILATE (ALSO KNOWN AS MERADIMATE IN OTC MONOGRAPH TERMINOLOGY)
Menthyl Anthranilate (CAS 134-09-8) is a cosmetic cosmetic ingredient functioning as UV Absorber. EU Regulation 1223/2009 status: permitted, max 5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 134-09-8 →
Auto-generated CPSR Part A draft with source citations
Function
UV Absorber
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
EU Max Conc.
5%
US US Status
permitted
US Notes
Allowed - FDA-approved OTC sunscreen active ingredient at concentrations up to 5% (21 CFR 352, Sunscreen Monograph); currently categorized as "insufficient data" (Category III) under the 2019 proposed sunscreen rule pending further safety evaluation
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Menthyl Anthranilate.
Calculate MoS for your specific formulation with the MoS Calculator.
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Cosmetic-Specific Mechanism
Category: UV filter
Receptor targets: ERα (limited)
LOEC: 10 µM
EU status: not approved
weak agonist
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
KR Korea MFDS Annex 2 (Restricted)
Category: UV Filter. Max: 5%.
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | permitted_uv_filter | 5 | All cosmetics |
| ASEAN | permitted_uv_filter | 5% | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
UV stabilizer
Expert Verdict
Expert safety assessment and concern-level summary for Menthyl Anthranilate.
Regulatory Flags
potential-allergen
Known Synonyms
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate
EINECS 205-129-8
UNII-J9QGD60OUZ
Chemical Function
UV stabilizer
Regulatory Lists
Canada; consumer_product; Substances in Products - Canada (4/2014)
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MERADIMATE
ChEMBL ID
CHEMBL1597075
Max Phase
2
Frequently Asked Questions
Is Menthyl Anthranilate allowed in the EU?
Menthyl Anthranilate EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Menthyl Anthranilate do in cosmetics?
Menthyl Anthranilate functions as: UV Absorber. It is classified as a cosmetic ingredient in our database. CAS number: 134-09-8.
Is Menthyl Anthranilate used outside cosmetics?
Menthyl Anthranilate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Menthyl Anthranilate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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