Is Macelignan safe in cosmetics?
Macelignan has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Macelignan
Also known as: UNII-8PP3614Z43, (8R,8'S)-7-(3,4-methylenedioxyphenyl)-7'-(4-hydroxy-3-methoxyphenyl)-8,8'-dimethylbutane, Phenol, 4-((2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl)-2-methoxy-
INCI: MACELIGNAN
Macelignan (CAS 107534-93-0) is a cosmetic cosmetic ingredient functioning as Antimicrobial, antioxidant, deodorant, oral care. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 107534-93-0 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, antioxidant, deodorant, oral care
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
4-[(2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol
InChIKey
QDDILOVMGWUNGD-UONOGXRCSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Allowed - not listed as prohibited or restricted under current FDA cosmetic regulations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Macelignan.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Biocide
Deodorizer
Expert Verdict
Expert safety assessment and concern-level summary for Macelignan.
Known Synonyms
UNII-8PP3614Z43
(8R,8'S)-7-(3,4-methylenedioxyphenyl)-7'-(4-hydroxy-3-methoxyphenyl)-8,8'-dimethylbutane
Phenol, 4-((2S,3R)-4-(1,3-benzodioxol-5-yl)-2,3-dimethylbutyl)-2-methoxy-
Chemical Function
Biocide
Antioxidant
Deodorizer
Regulatory Lists
Canada; pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
AUSTROBAILIGNAN 6
ChEMBL ID
CHEMBL254071
Frequently Asked Questions
Is Macelignan allowed in the EU?
Macelignan EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Macelignan do in cosmetics?
Macelignan functions as: Antimicrobial, antioxidant, deodorant, oral care. It is classified as a cosmetic ingredient in our database. CAS number: 107534-93-0.
Is Macelignan used outside cosmetics?
Macelignan also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Macelignan compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Viscosity Controlling
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