Is Keratinase safe in cosmetics?
Keratinase has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Keratinase
INCI: KERATINASE
Keratinase (CAS 9025-41-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning (proteolytic enzyme). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9025-41-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning (proteolytic enzyme)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Keratinase.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
exfoliant
{"cas_number": "9036-09-3", "ingredient_class": "enzymatic_exfoliant", "chemical_subclass": "proteolytic_enzyme/bacterial_enzyme", "pH_dependent_activity": "yes", "optimal_pH_range": "7.5-9.0", "penetration_depth": "stratum_corneum", "mechanism_of_action": "keratin_dissolution", "target_bonds": "keratin_crosslinks", "onset_of_action": "minutes", "comedolytic": "yes", "anti_aging_mechanism": "resur…
Expert Verdict
Expert safety assessment and concern-level summary for Keratinase.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Keratinase allowed in the EU?
Keratinase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Keratinase do in cosmetics?
Keratinase functions as: Skin conditioning (proteolytic enzyme). It is classified as a cosmetic ingredient in our database. CAS number: 9025-41-6.
Compliance Tools
Check Keratinase compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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