NOAEL Studies Cosmetic Ingredient

Isostearyl Neopentanoate NOAEL Studies

INCI: ISOSTEARYL NEOPENTANOATE

CAS: 58958-60-4

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - reproduction developmental GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac3ee4b0a7c65d1be1e0; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17586/7/9/3?documentUUID=837bc168-3f30-4714-8c97-52df08bbb229; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15822682:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_4d38d672ce97d0c3cea91c6bb7e538e0
ToxValDB_ECHA_IUCLID NOAEL >=3460 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae7de4b0a7c65d1c96f9; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17586/7/6/2?documentUUID=837bc168-3f30-4714-8c97-52df08bbb229; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15844122:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e56f54ece6e9e8c09881731d0553b6db
ToxValDB_ECHA_IUCLID NOAEL =5500 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab1ae4b0a7c65d1b8d0c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17586/7/9/2?documentUUID=837bc168-3f30-4714-8c97-52df08bbb229; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID:15857637:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7aa6a2dd9c64ab0e3ead46d04b3aa66d
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 411THY156Q UNII - - - chemical {"approval_status":null,"molecular_formula":"C23H46O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"411THY156Q"}
openFDA substances FDA UNII substance identifier 411THY156Q UNII - - - chemical {"approval_status":null,"molecular_formula":"C23H46O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"411THY156Q"}
openFDA substances FDA UNII substance identifier 411THY156Q UNII - - - chemical {"approval_status":null,"molecular_formula":"C23H46O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"411THY156Q"}
openFDA substances FDA UNII substance identifier 411THY156Q UNII - - - chemical {"approval_status":null,"molecular_formula":"C23H46O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"411THY156Q"}