NOAEL Studies Cosmetic Ingredient

Isopropylideneglycerol NOAEL Studies

INCI: ISOPROPYLIDENEGLYCEROL

CAS: 100-79-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEC >5000 mg/m3 Rat inhalation acute; 3 hours acute QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66059786e4b063812d6fa765; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/25906/7/6/3?documentUUID=27aab4ce-8d0c-4d75-819f-ce3ae9ee761a; YEAR=2014; ORIGINAL_YEAR=2014; STUDY_GROUP=ECHA IUCLID:15828671:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d8ba9efc1f613090a8d794fe758b3eae
ToxValDB_ECHA_IUCLID NOAEL =300 mg/kg bw/day Rabbit oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabace4b0a7c65d1bb2f7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/25906/7/9/3?documentUUID=27aab4ce-8d0c-4d75-819f-ce3ae9ee761a; YEAR=2014; ORIGINAL_YEAR=2014; TOXICOLOGICAL_EFFECT=maternal: food consumption and compound intake; TOXICOLOGICAL_EFFECT_CATEGORY=food and/or water consumption; STUDY_GROUP=ECHA IUCLID:15823311:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_e8d770831fba1d18d07fe2f4bb2ba849
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabace4b0a7c65d1bb2fa; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/25906/7/9/3?documentUUID=27aab4ce-8d0c-4d75-819f-ce3ae9ee761a; YEAR=2014; ORIGINAL_YEAR=2014; STUDY_GROUP=ECHA IUCLID:15823868:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_93c16367ab4c957cbc08b54054309a38
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 3XK098O8ZW UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H12O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3XK098O8ZW"}
openFDA substances FDA UNII substance identifier 3XK098O8ZW UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H12O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3XK098O8ZW"}
openFDA substances FDA UNII substance identifier 3XK098O8ZW UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H12O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3XK098O8ZW"}
openFDA substances FDA UNII substance identifier 3XK098O8ZW UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H12O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3XK098O8ZW"}