Is Isopropyl Nicotinate safe in cosmetics?
Isopropyl Nicotinate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Isopropyl Nicotinate
Also known as: EINECS 209-043-1, Nicotinic acid, isopropyl ester, NSC 6860, iso-Propyl nicotinate, UNII-900M2HXF1R
INCI: ISOPROPYL NICOTINATE
Isopropyl Nicotinate (CAS 553-60-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent (vasodilator / rubefacient). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 553-60-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent (vasodilator / rubefacient)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
propan-2-yl pyridine-3-carboxylate
InChIKey
VSRSQDMWBSKNSF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Permitted — no specific CFR prohibition for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isopropyl Nicotinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Isopropyl Nicotinate.
Known Synonyms
EINECS 209-043-1
Nicotinic acid, isopropyl ester
NSC 6860
iso-Propyl nicotinate
UNII-900M2HXF1R
Chemical Function
Softener and conditioner
Flavouring and nutrient
Regulatory Lists
detected; Europe; Personal care - sexual wellness
detected; Europe; Personal care - sexual wellness
Europe; Personal care - sexual wellness
Europe
Frequently Asked Questions
Is Isopropyl Nicotinate allowed in the EU?
Isopropyl Nicotinate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isopropyl Nicotinate do in cosmetics?
Isopropyl Nicotinate functions as: Skin conditioning agent (vasodilator / rubefacient). It is classified as a cosmetic ingredient in our database. CAS number: 553-60-6.
Is Isopropyl Nicotinate used outside cosmetics?
Isopropyl Nicotinate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isopropyl Nicotinate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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