Is Isodecyl Oleate safe in cosmetics?
Isodecyl Oleate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 2 toxicological study endpoint(s) are available in our database.
Isodecyl Oleate
Also known as: 9-Octadecenoic acid (9Z)-, isodecyl ester, 9-Octadecenoic acid (Z)-, isodecyl ester, Oleic acid, isodecyl ester, Ceraphyl 140A, OLEATE, ISODECYL (+3 more)
INCI: ISODECYL OLEATE
Isodecyl Oleate (CAS 59231-34-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning, Emollient. Reported NOAEL =300 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 59231-34-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, Emollient
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
8-methylnonyl (Z)-octadec-9-enoate
InChIKey
ODMZDMMTKHXXKA-QXMHVHEDSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR reviewed (1982) — concluded safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isodecyl Oleate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Isodecyl Oleate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =300 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Stabilizing agent
Expert Verdict
Expert safety assessment and concern-level summary for Isodecyl Oleate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isodecyl Oleate by CAS number or substance name.
Studies
2
Lowest NOAEL
300 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
9-Octadecenoic acid (9Z)-, isodecyl ester
9-Octadecenoic acid (Z)-, isodecyl ester
Oleic acid, isodecyl ester
Ceraphyl 140A
OLEATE, ISODECYL
Z)-9-Octadecenoic acid isodecyl ester
9-Octadecenoic acid, isodecyl ester, (Z)-
EINECS No.: 261-673-6
Chemical Function
Softener and conditioner
Stabilizing agent
Humectant
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isodecyl Oleate allowed in the EU?
Isodecyl Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isodecyl Oleate do in cosmetics?
Isodecyl Oleate functions as: Skin conditioning, Emollient. It is classified as a cosmetic ingredient in our database. CAS number: 59231-34-4.
What is the NOAEL for Isodecyl Oleate?
The NOAEL (No Observed Adverse Effect Level) for Isodecyl Oleate is =300 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 2 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.
Is Isodecyl Oleate used outside cosmetics?
Isodecyl Oleate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isodecyl Oleate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
Excellent
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
Excellent
Same category
Skin conditioning (emollient)
Acetyl Ornithine
Excellent
Same category
Emollient
Acetyl Proline
Excellent
Same category
Emollient
Acetyl Triethylhexyl Citrate
Excellent
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
Excellent
Same category
Plasticiser, Skin Conditioning (Emoll...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
(ARCTIUM LAPPA/CARROT/COLOCASIA ESCULENTA/DIOSCOREA BATATAS/GARLIC/GINGER/IPOMOEA BATATAS/NELUMBO NUCIFERA/ONION/POTATO BULBS)/(CHESTNUT/CITRUS UNSHIU/EGGPLANT/FIG/GRAPE/KIWI/LYCOPERSICON ESCULENTUM/MALUS PUMILA/MUME/PEACH/PLUM/PUMPKIN/PYRUS SEROTINA/RADISH/ZIZIPHUS JUJUBA FRUIT)/(ALLIUM TUBEROSUM/ALOE BARBADENSIS/ANGELICA UTILIS/BRASSICA OLERACEA ACEPHALA/CABBAGE/CELERY/SACCHARINA JAPONICA/UNDARIA PINNATIFIDA LEAF)/(ALLIUM FISTULOSUM/ENTEROMORPHA COMPRESSA/OENANTHE JAVANICA STALK)/LENTINULA EDODES/SUCROSE FERMENT FILTRATE
Good
Similar safety
Humectant, Skin Conditioning - Humect...
DEA-Linoleate
Moderate
Chemical family
Emulsifying, surfactant
Isodecyl Isononanoate
Excellent
Chemical family
Skin conditioning agent — emollient
Isotridecyl Isononanoate
Moderate
Chemical family
Emollient, skin conditioning, smoothi...
Is Isodecyl Oleate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isodecyl Oleate in your formulation.