Is Ipriflavone safe in cosmetics?
Ipriflavone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ipriflavone
Also known as: BRN 4754346, Ipriflavona, Ipriflavonum, UNII-80BJ7WN25Z, 7-(1-methylethoxy)-3-phenyl-4H-1-benzopyran-4-one (+2 more)
INCI: IPRIFLAVONE
Ipriflavone (CAS 35212-22-7) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 35212-22-7 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-phenyl-7-propan-2-yloxychromen-4-one
InChIKey
SFBODOKJTYAUCM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Used primarily as a pharmaceutical ingredient for osteoporosis; cosmetic use is niche; no FDA restrictions on topical application
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ipriflavone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Expert Verdict
Expert safety assessment and concern-level summary for Ipriflavone.
Regulatory Flags
isoflavone
anti-aging
antioxidant
Known Synonyms
BRN 4754346
Ipriflavona
Ipriflavonum
UNII-80BJ7WN25Z
7-(1-methylethoxy)-3-phenyl-4H-1-benzopyran-4-one
7-isopropoxyisoflavone
FL-113
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
Frequently Asked Questions
Is Ipriflavone allowed in the EU?
Ipriflavone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ipriflavone do in cosmetics?
Ipriflavone functions as: Antioxidant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 35212-22-7.
Compliance Tools
Check Ipriflavone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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