Is Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) safe in cosmetics?
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin)
Also known as: 1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1-methylpropyl ester, Picaridin, Butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate, Autan, Autan Repel (+15 more)
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) (CAS 119515-38-7) is a cosmetic cosmetic ingredient functioning as Biocide. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 119515-38-7 →
Auto-generated CPSR Part A draft with source citations
Function
Biocide
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate
InChIKey
QLHULAHOXSSASE-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
EPA-registered pesticide. If used in cosmetic product with insect-repellent claims, FDA/EPA dual jurisdiction applies.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin).
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Evidence for Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Expert Verdict
Expert safety assessment and concern-level summary for Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin).
Known Synonyms
1-Piperidinecarboxylic acid, 2-(2-hydroxyethyl)-, 1-methylpropyl ester
Picaridin
Butan-2-yl 2-(2-hydroxyethyl)piperidine-1-carboxylate
Autan
Autan Repel
Isobutyl 2-(2-hydroxyethyl)-1-piperidinecarboxylate
Natrapel
KBR 3023
sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate\Icaridine
icaridin
1-methylpropyl 2-(2-hydroxyethyl)piperidine-1-carboxylate
Acido 1-Piperidinecarboxilic, 2 - (2-hidroxietil) -, 1-metilpropil ester
1-(1-Methylpropoxycarbonyl)-2-(2-hydroxyethyl)piperidine
1-Methylpropyl 2-(2-hydroxyethyl)-1-piperidinecarboxylate
Bayrepel
Icaridine
Icaridina
Pikaridin
Propidine
Cutter Advanced
Chemical Function
Biocide
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Australia
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ICARIDIN
ChEMBL ID
CHEMBL2104314
Max Phase
2
Frequently Asked Questions
Is Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) allowed in the EU?
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) do in cosmetics?
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) functions as: Biocide. It is classified as a cosmetic ingredient in our database. CAS number: 119515-38-7.
Is Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) used outside cosmetics?
Hydroxyethyl Isobutyl Piperidine Carboxylate (Icaridin/Picaridin) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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HYDRASTIS CANADENSIS EXTRACT
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Fragrance, Skin Conditioning
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