NOAEL Studies
Cosmetic Ingredient
Hydrogenated Polydecene NOAEL Studies
INCI: HYDROGENATED POLYDECENE
CAS: 68037-01-4
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ToxValDB_ECHA_IUCLID 5 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =1000 | mg/kg bw/day | Rat | oral | chronic; 91 days | chronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead7ee4b0a7c65d1c478d; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/8356?documentUUID=2bb180ed-98b3-4f7b-8059-643243647c11; YEAR=2009; ORIGINAL_YEAR=2009; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850769_15850770_15850771_15850772_15850773_15850774_15850775_15850776_15850777_15850778_15850779_15850780_15850781:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_03cb91595364114908374934f6ea4002 |
| ToxValDB_ECHA_IUCLID | NOAEL | =4159.4 | mg/kg bw/day | Rat | oral | subchronic; 13 weeks | subchronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf4fe4b0a7c65d1cd561; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/12597?documentUUID=b853f4ce-7575-4a00-97a0-4522d749d8ce; YEAR=1995; ORIGINAL_YEAR=1995; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850782_15850783_15850784_15850785_15850786_15850787_15850788_15850789_15850790_15850791_15850792_15850793_15850794:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_2f42e11942b7f08d79d0ff65ce8d96ea |
| ToxValDB_ECHA_IUCLID | NOAEL | =4619.9 | mg/kg bw/day | Rat | oral | subchronic; 13 weeks | subchronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead7ee4b0a7c65d1c4772; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/2221/7/6/2?documentUUID=75438957-1661-43b9-8385-3b527244cad0; YEAR=2013; ORIGINAL_YEAR=2013; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850795_15850796_15850797_15850798_15850799_15850800_15850801_15850802_15850803_15850804_15850805_15850806_15850807:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_2cd260ad969066bad9f7634e2259b772 |
| ToxValDB_ECHA_IUCLID | NOAEL | =6245 | mg/kg bw/day | Rat | oral | short-term; 29 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae8ce4b0a7c65d1c9c41; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/26744/7/6/2?documentUUID=fb4cb45c-7bc1-462b-b90c-4da07e256271; YEAR=1997; ORIGINAL_YEAR=1997; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850808_15850809_15850810_15850811_15850812_15850813_15850814_15850815_15850816_15850817_15850818_15850819_15850820:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_094a9cae20e8e58c40b89877e708c74e |
| ToxValDB_ECHA_IUCLID | NOAEL | =6771 | mg/kg bw/day | Rat | oral | short-term; 29 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead7ee4b0a7c65d1c4789; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/8356?documentUUID=2bb180ed-98b3-4f7b-8059-643243647c11; YEAR=2009; ORIGINAL_YEAR=2009; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15850821_15850822_15850823_15850824_15850825_15850826_15850827_15850828_15850829_15850830_15850831_15850832_15850833:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_12d475f120cfdd5323142a573fb44014 |
ToxValDB_WHO_JECFA_ADI 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_WHO_JECFA_ADI | ADI | <=6 | mg/kg | Human | oral | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/650afec9e4b0d99f5a880cec; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/; SUBSOURCE_URL=https://apps.who.int/food-additives-contaminants-jecfa-database/Home/Chemical/722; YEAR=2001; ORIGINAL_YEAR=2001; STUDY_GROUP=WHO JECFA ADI:15715562:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_008f478fea2351dd57da9f24db365647 |
openFDA substances 24 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 048B98MT5O | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H42","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"048B98MT5O"} |
| openFDA substances | FDA UNII substance identifier | 048B98MT5O | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H42","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"048B98MT5O"} |
| openFDA substances | FDA UNII substance identifier | 048B98MT5O | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H42","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"048B98MT5O"} |
| openFDA substances | FDA UNII substance identifier | 048B98MT5O | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H42","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"048B98MT5O"} |
| openFDA substances | FDA UNII substance identifier | 4U179ML4TJ | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4U179ML4TJ"} |
| openFDA substances | FDA UNII substance identifier | 4U179ML4TJ | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4U179ML4TJ"} |
| openFDA substances | FDA UNII substance identifier | 4U179ML4TJ | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4U179ML4TJ"} |
| openFDA substances | FDA UNII substance identifier | 4U179ML4TJ | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4U179ML4TJ"} |
| openFDA substances | FDA UNII substance identifier | 4YI0729529 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4YI0729529"} |
| openFDA substances | FDA UNII substance identifier | 4YI0729529 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4YI0729529"} |
| openFDA substances | FDA UNII substance identifier | 4YI0729529 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4YI0729529"} |
| openFDA substances | FDA UNII substance identifier | 4YI0729529 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"4YI0729529"} |
| openFDA substances | FDA UNII substance identifier | 75Y1X69O7I | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"75Y1X69O7I"} |
| openFDA substances | FDA UNII substance identifier | 75Y1X69O7I | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"75Y1X69O7I"} |
| openFDA substances | FDA UNII substance identifier | 75Y1X69O7I | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"75Y1X69O7I"} |
| openFDA substances | FDA UNII substance identifier | 75Y1X69O7I | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"75Y1X69O7I"} |
| openFDA substances | FDA UNII substance identifier | CQ4IKK1766 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"CQ4IKK1766"} |
| openFDA substances | FDA UNII substance identifier | CQ4IKK1766 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"CQ4IKK1766"} |
| openFDA substances | FDA UNII substance identifier | CQ4IKK1766 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"CQ4IKK1766"} |
| openFDA substances | FDA UNII substance identifier | CQ4IKK1766 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"CQ4IKK1766"} |
| openFDA substances | FDA UNII substance identifier | U333RI6EB7 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"U333RI6EB7"} |
| openFDA substances | FDA UNII substance identifier | U333RI6EB7 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"U333RI6EB7"} |
| openFDA substances | FDA UNII substance identifier | U333RI6EB7 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"U333RI6EB7"} |
| openFDA substances | FDA UNII substance identifier | U333RI6EB7 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"U333RI6EB7"} |