Is Hydrogenated Phosphatidylcholine safe in cosmetics?
Hydrogenated Phosphatidylcholine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Emollient
Hydrogenated Phosphatidylcholine
Also known as: Phosphatidylcholines, soya, hydrogenated, EINECS 306-549-5, Hydrogenated soybean lecithin, Phospholipon 90N, Coatsome NC 21E
INCI: HYDROGENATED PHOSPHATIDYLCHOLINE
Hydrogenated Phosphatidylcholine (CAS 97281-48-6) is a cosmetic emollient functioning as Emulsifying, skin conditioning, penetration enhancer. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 97281-48-6 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifying, skin conditioning, penetration enhancer
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2,3-di(octadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
InChIKey
NRJAVPSFFCBXDT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Final Report (2015) concluded safe in present practices of use and concentration, superseding 2001 report's 15% concentration cap. Lecithin (parent mixture) is GRAS under 21 CFR 184.1400. Hydrogenated soy lecithin listed as inactive ingredient in inhaled aerosols (pending FDA approval, max 0.28%).
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrogenated Phosphatidylcholine.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Hydrogenated Phosphatidylcholine.
Known Synonyms
Phosphatidylcholines, soya, hydrogenated
EINECS 306-549-5
Hydrogenated soybean lecithin
Phospholipon 90N
Coatsome NC 21E
Chemical Function
Softener and conditioner
Emulsifier
Regulatory Lists
Canada; pharmaceutical
Frequently Asked Questions
Is Hydrogenated Phosphatidylcholine allowed in the EU?
Hydrogenated Phosphatidylcholine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrogenated Phosphatidylcholine do in cosmetics?
Hydrogenated Phosphatidylcholine functions as: Emulsifying, skin conditioning, penetration enhancer. It is classified as a Emollient in our database. CAS number: 97281-48-6.
Is Hydrogenated Phosphatidylcholine used outside cosmetics?
Hydrogenated Phosphatidylcholine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hydrogenated Phosphatidylcholine compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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