Is Hexyldecanoic Acid (2-Hexyldecanoic Acid) safe in cosmetics?
Hexyldecanoic Acid (2-Hexyldecanoic Acid) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hexyldecanoic Acid (2-Hexyldecanoic Acid)
Also known as: Decanoic acid, 2-hexyl-, 4-02-00-01189, C16 Guerbet fatty acid, BRN 1777217, EINECS 246-885-9 (+3 more)
INCI: HEXYLDECANOIC ACID
Hexyldecanoic Acid (2-Hexyldecanoic Acid) (CAS 25354-97-6) is a cosmetic cosmetic ingredient functioning as Surfactant / skin-conditioning agent (emollient). NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 25354-97-6 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant / skin-conditioning agent (emollient)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-hexyldecanoic acid
InChIKey
JMOLZNNXZPAGBH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not in 21 CFR 700/250 prohibited/restricted lists
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyldecanoic Acid (2-Hexyldecanoic Acid).
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Hexyldecanoic Acid (2-Hexyldecanoic Acid) across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Emulsifier
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for Hexyldecanoic Acid (2-Hexyldecanoic Acid).
Known Synonyms
Decanoic acid, 2-hexyl-
4-02-00-01189
C16 Guerbet fatty acid
BRN 1777217
EINECS 246-885-9
7-Pentadecanecarboxylic acid
2-Hexyldecansaeure
UNII-49M19XFI8B
Chemical Function
Surfactant (surface active agent)
Emulsifier
Cleaning agent
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182660
Frequently Asked Questions
Is Hexyldecanoic Acid (2-Hexyldecanoic Acid) allowed in the EU?
Hexyldecanoic Acid (2-Hexyldecanoic Acid) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyldecanoic Acid (2-Hexyldecanoic Acid) do in cosmetics?
Hexyldecanoic Acid (2-Hexyldecanoic Acid) functions as: Surfactant / skin-conditioning agent (emollient). It is classified as a cosmetic ingredient in our database. CAS number: 25354-97-6.
Is Hexyldecanoic Acid (2-Hexyldecanoic Acid) used outside cosmetics?
Hexyldecanoic Acid (2-Hexyldecanoic Acid) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyldecanoic Acid (2-Hexyldecanoic Acid) compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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