Is Hexyl Nicotinate safe in cosmetics?
Hexyl Nicotinate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hexyl Nicotinate
Also known as: 3-Pyridinecarboxylic acid, hexyl ester, EINECS 245-767-4, Nicotherm, Nicotinic acid, hexyl ester, NSC 72758 (+3 more)
INCI: HEXYL NICOTINATE
Hexyl Nicotinate (CAS 23597-82-2) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent (rubefacient/vasodilator); used in sun-tanning,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 23597-82-2 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent (rubefacient/vasodilator); used in sun-tanning, slimming, and warming products
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
hexyl pyridine-3-carboxylate
InChIKey
RVYGVBZGSFLJKH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no 21 CFR 700 restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyl Nicotinate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Hexyl Nicotinate.
Known Synonyms
3-Pyridinecarboxylic acid, hexyl ester
EINECS 245-767-4
Nicotherm
Nicotinic acid, hexyl ester
NSC 72758
Nicotinsaeure-n-hexylester
Hexyl nicotinoate
UNII-BN07PB44IV
Chemical Function
Softener and conditioner
Anti-static agent
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1474122
Frequently Asked Questions
Is Hexyl Nicotinate allowed in the EU?
Hexyl Nicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyl Nicotinate do in cosmetics?
Hexyl Nicotinate functions as: Skin conditioning agent (rubefacient/vasodilator); used in sun-tanning, slimming, and warming products. It is classified as a cosmetic ingredient in our database. CAS number: 23597-82-2.
Is Hexyl Nicotinate used outside cosmetics?
Hexyl Nicotinate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyl Nicotinate compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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