Is Hexapeptide-43 safe in cosmetics?
Hexapeptide-43 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Hexapeptide-43
INCI: HEXAPEPTIDE-43
Hexapeptide-43 (CAS | Hexapeptide-40) is a cosmetic cosmetic ingredient functioning as Humectant, skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS | Hexapeptide-40 →
Auto-generated CPSR Part A draft with source citations
Function
Humectant, skin conditioning agent
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not listed as prohibited or restricted in 21 CFR; no CIR monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexapeptide-43.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Hexapeptide-43.
Frequently Asked Questions
Is Hexapeptide-43 allowed in the EU?
Hexapeptide-43 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-43 do in cosmetics?
Hexapeptide-43 functions as: Humectant, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: | Hexapeptide-40.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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