NOAEL Studies Cosmetic Ingredient

1,2-Hexanediol NOAEL Studies

INCI: 1,2-HEXANEDIOL

CAS: 6920-22-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOAEL =1000 mg/kg bw/day Rat dermal chronic; 93 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61ee6e4b096bca877b839; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11614/7/6/4?documentUUID=6011bfdf-19a9-48b6-a683-80431c7a6248; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826681_15826682:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c17092977a7dbd1f5fc372004c67528e
ToxValDB_ECHA_IUCLID NOAEL =300 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac62e4b0a7c65d1bec8b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11614/7/9/3?documentUUID=6011bfdf-19a9-48b6-a683-80431c7a6248; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15822406:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_1e2a1237093227d20bdfd0d2933ad57f
ToxValDB_ECHA_IUCLID NOAEL =700 mg/kg bw/day Rat dermal chronic; 93 days chronic QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61ee6e4b096bca877b839; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/11614/7/6/4?documentUUID=6011bfdf-19a9-48b6-a683-80431c7a6248; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826681_15826682:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d9f78b514fb7fd41afaf5ccb3248a14a
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =123 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15632521:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_756b9dd3ddaebbef3a5e953ccb58bda3
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier TR046Y3K1G UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TR046Y3K1G"}
openFDA substances FDA UNII substance identifier TR046Y3K1G UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TR046Y3K1G"}
openFDA substances FDA UNII substance identifier TR046Y3K1G UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TR046Y3K1G"}
openFDA substances FDA UNII substance identifier TR046Y3K1G UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TR046Y3K1G"}