Is Heptapeptide-27 safe in cosmetics?
Heptapeptide-27 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Heptapeptide-27
INCI: HEPTAPEPTIDE-27
Heptapeptide-27 (CAS Not publicly listed in CosIng or major databases) is a cosmetic cosmetic ingredient functioning as Skin conditioning (signaling peptide; upregulates filaggrin and loricrin). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not publicly listed in CosIng or major databases →
Auto-generated CPSR Part A draft with source citations
CAS Number
Not publicly listed in CosIng or major databases
View industrial chemical safety profile →
Function
Skin conditioning (signaling peptide; upregulates filaggrin and loricrin)
Safety Rating
MODERATE
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Not specifically restricted; permitted for cosmetic use under general FDA cosmetics framework (no monograph or prohibition)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Heptapeptide-27.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Heptapeptide-27.
Frequently Asked Questions
Is Heptapeptide-27 allowed in the EU?
Heptapeptide-27 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Heptapeptide-27 do in cosmetics?
Heptapeptide-27 functions as: Skin conditioning (signaling peptide; upregulates filaggrin and loricrin). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed in CosIng or major databases.
Compliance Tools
Check Heptapeptide-27 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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