Is HDI Isocyanurate Trimer safe in cosmetics?
HDI Isocyanurate Trimer has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: restricted.
Moderate
Cosmetic Ingredient
HDI Isocyanurate Trimer
Also known as: EINECS 223-242-0, (2,4,6-Trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate, (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethyleneisocyanate), 1,3,5-tris(6-isocyanatohexyl)-1,3,5-triazine-2,4,6 (1H,3H,5H)-trione, 1,3,5-tris(isocyanatohexamethylene)isocyanurate (+5 more)
INCI: HDI ISOCYANURATE TRIMER
HDI Isocyanurate Trimer (CAS 3779-63-3) is a cosmetic cosmetic ingredient functioning as Film forming, binding, crosslinker (precursor/raw material). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 3779-63-3 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
HDI Isocyanurate Trimer is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H332, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film forming, binding, crosslinker (precursor/raw material)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
1,3,5-tris(6-isocyanatohexyl)-1,3,5-triazinane-2,4,6-trione
InChIKey
KCZQSKKNAGZQSZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Permitted; not specifically restricted in cosmetics; FCN noted for food-contact polymer applications
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for HDI Isocyanurate Trimer.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chemical reaction regulator
Hardener
No specific technical function
Expert Verdict
Expert safety assessment and concern-level summary for HDI Isocyanurate Trimer.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 223-242-0
(2,4,6-Trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate
(2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethyleneisocyanate)
1,3,5-tris(6-isocyanatohexyl)-1,3,5-triazine-2,4,6 (1H,3H,5H)-trione
1,3,5-tris(isocyanatohexamethylene)isocyanurate
HDI-IC
hexamethylene diisocyanate isocyanurate
trimeric hexamethylene diisocyanate
tris(6-isocyanatohexyl) isocyanurate
1,3,5-tris(6-isocyanatohexyl)-1,3,5-triazin-2,4,6-trione
Chemical Function
Hardener
Chemical reaction regulator
No specific technical function
Australian Status
AICIS status: listed
Frequently Asked Questions
Is HDI Isocyanurate Trimer allowed in the EU?
HDI Isocyanurate Trimer EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does HDI Isocyanurate Trimer do in cosmetics?
HDI Isocyanurate Trimer functions as: Film forming, binding, crosslinker (precursor/raw material). It is classified as a cosmetic ingredient in our database. CAS number: 3779-63-3.
Is HDI Isocyanurate Trimer used outside cosmetics?
HDI Isocyanurate Trimer also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does HDI Isocyanurate Trimer have different safety status in cosmetics vs industrial chemicals?
HDI Isocyanurate Trimer is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H332, H335).
Compliance Tools
Check HDI Isocyanurate Trimer compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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