Is HC Blue No. 11 safe in cosmetics?
HC Blue No. 11 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
HC Blue No. 11
Also known as: UNII-83ZYM95HPE, Ethanol, 2,2'-((4-((2-methoxyethyl)amino)-3-nitrophenyl)imino)bis-, monohydrochloride, Colorex HCB11
INCI: HC BLUE NO. 11
HC Blue No. 11 (CAS 910463-51-3) is a cosmetic cosmetic ingredient functioning as Hair dyeing (direct/semi-permanent nitro dye). EU Regulation 1223/2009 status: prohibited, max 3.0%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 910463-51-3 →
Auto-generated CPSR Part A draft with source citations
Function
Hair dyeing (direct/semi-permanent nitro dye)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2-[N-(2-hydroxyethyl)-4-(2-methoxyethylamino)-3-nitroanilino]ethanol;hydrochloride
InChIKey
GTMWPZKEYRLDJV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
EU Max Conc.
3.0%
US US Status
permitted
US Notes
Permitted under coal tar hair dye exemption (21 CFR 740.17)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for HC Blue No. 11.
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for HC Blue No. 11 based on clinical patch test studies and IFRA standards.
Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis
Source: SCCS; IVDK
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
No longer valid
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
2 property records from structured ingredient metadata.
allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "dye", "cross_reactivity_group": "para-amino-group", "patch_test_frequency_pct": "0.2", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "SCCS; IVDK"}
hair_dye
{"cas_number": "23920-15-2", "ingredient_class": "direct_dye", "chemical_class": "nitro", "molecular_weight_Da": "271.27", "color_result_on_hair": "Violet-blue", "shade_range": "fashion_color", "primary_function": "direct_deposit", "requires_developer": "no", "lift_capability_levels": "0", "deposit_only": "yes", "permanence": "semi_permanent", "wash_fastness_shampoos": "6-12", "light_fastness": "m…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Expert Verdict
Expert safety assessment and concern-level summary for HC Blue No. 11.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to HC Blue No. 11 by CAS number or substance name.
Studies
28
Lowest NOAEL
0.046
Highest NOAEL
1275
Units vary across source rows: mg/kg bw/day, mg/kg bw
SCCS_vision_codex
Known Synonyms
UNII-83ZYM95HPE
Ethanol, 2,2'-((4-((2-methoxyethyl)amino)-3-nitrophenyl)imino)bis-, monohydrochloride
Colorex HCB11
Chemical Function
Dye
Frequently Asked Questions
Is HC Blue No. 11 allowed in the EU?
HC Blue No. 11 EU regulatory status: prohibited. Maximum allowed concentration: 3.0%. This is based on EU Regulation 1223/2009 and its amendments.
What does HC Blue No. 11 do in cosmetics?
HC Blue No. 11 functions as: Hair dyeing (direct/semi-permanent nitro dye). It is classified as a cosmetic ingredient in our database. CAS number: 910463-51-3.
Compliance Tools
Check HC Blue No. 11 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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