Is Glycol Palmitate safe in cosmetics?
Glycol Palmitate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Emulsifier
Glycol Palmitate
INCI: GLYCOL PALMITATE
Glycol Palmitate (CAS 4219-49-2) is a cosmetic emulsifier functioning as Surfactant-Emulsifying, Opacifying, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 4219-49-2 →
Auto-generated CPSR Part A draft with source citations
Function
Surfactant-Emulsifying, Opacifying, Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-hydroxyethyl hexadecanoate
InChIKey
BXCRLBBIZJSWNS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No individual CIR assessment. Read-across from Glycol Stearate/Distearate (CIR safe up to 10%).
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycol Palmitate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "3.5", "co_emulsifier_pairs": "sorbitan_stearate,glyceryl_stearate", "optimal_oil_phase_pct": "65-88", "optimal_water_phase_pct": "12-35", "droplet_size_range_um": "8-60", "creaming_resistance": "poor", "coalescence_resistance": "excellent", "ostwald_ripening_resistance": "excellent", "freeze_thaw_stability": "moderate", "rheology_m…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Opacifer
Softener and conditioner
Stabilizing agent
Surfactant (surface active agent)
Regulatory List Membership (1)
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Glycol Palmitate.
Regulatory Flags
epa_safer_alternative
Chemical Function
Softener and conditioner
Emulsifier
Opacifer
Stabilizing agent
Surfactant (surface active agent)
Regulatory Lists
SCIL (9/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Glycol Palmitate allowed in the EU?
Glycol Palmitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycol Palmitate do in cosmetics?
Glycol Palmitate functions as: Surfactant-Emulsifying, Opacifying, Skin Conditioning. It is classified as a Emulsifier in our database. CAS number: 4219-49-2.
Is Glycol Palmitate used outside cosmetics?
Glycol Palmitate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glycol Palmitate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
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Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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