Excellent Emollient

Glyceryl Oleate

Also known as: 9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol, EINECS 247-038-6, Emery oleic acid ester 2221, Glycerol, 1-mono (9-octa-decenoate), Glycerol oleate (+6 more)

INCI: GLYCERYL OLEATE

Glyceryl Oleate (CAS 25496-72-4) is a cosmetic emollient functioning as Emollient, Emulsifying, Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.

View industrial chemical safety profile for CAS 25496-72-4 →

Auto-generated CPSR Part A draft with source citations
Function
Emollient, Emulsifying, Skin Conditioning
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
C21H40O4
MW
356.5 g/mol
PubChem CID
5283468
IUPAC Name
2,3-dihydroxypropyl (Z)-octadec-9-enoate
InChIKey
RZRNAYUHWVFMIP-KTKRTIGZSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes GRAS for food use

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Glyceryl Oleate.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

9 property records from structured ingredient metadata.

comedogenicity_detail
{"comedogenicity_rating": "2", "irritancy_rating": "1", "skin_type_suitability": "dry,combination,normal", "acne_safe": "caution", "source": "Emulsifier"}
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
emulsifier
{"cas_number": "25496-72-4", "ingredient_class": "W/O_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "3.8", "HLB_required_for_oil_phase": "3-6", "emulsion_type_primary": "W/O", "droplet_size_typical_um": "5-10", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "liquid_crystal_formation": "low", "lamellar_phase…
emulsion_hlb
{"hlb_value": "3.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.65-0.85", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "oleyl_alcohol,sorbitan_oleate", "optimal_oil_phase_pct": "55-85", "optimal_water_phase_pct": "15-45", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.5-10.5", "viscos…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "moisture", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "ker…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "9.0", "stable_ph_min": "3.5", "stable_ph_max": "10.0", "ph_dependent_function": "Natural O/W emulsifier", "formulation_note": "PEG-free emulsifier", "source": "Formulation literature"}
sensory
{"silky": "medium", "smooth, glides easily": "smooth, emulsifies", "dry-touch, non-greasy": "soft, smooth", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "high", "no": "no", "yes": "no", "light-diffusing": "luminous", "1.40": "1.47", "transparent": "translucent", "colorless": "amber", "excellent": "good", "light": "medium", "synthetic": "botanical"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_value": "5.0", "soluble_in": "oils, ethanol", "insoluble_in": "water", "log_p": "4.2", "appearance": "amber liquid", "source": "Oleon"}

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Regulatory (2)
JECFA Number
919
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
GLYCERYL MONOOLEATE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | TRS 913-JECFA 59/112 | FAS 48-JECFA 57/333 (2001)
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive Anti-caking agent Anti-static agent Drier Emulsifier Flavouring and nutrient Flow promoter Fragrance Heat stabilizer Humectant
Regulatory List Membership (3)
IFRA Fragrance Transparency List EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Glyceryl Oleate.

Regulatory Flags

eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Known Synonyms

9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol EINECS 247-038-6 Emery oleic acid ester 2221 Glycerol, 1-mono (9-octa-decenoate) Glycerol oleate Oleoylglycerol 1,2,3-Propanetriol mono((Z)-9-octadecenoate) Rikemal O 71D Monomuls 90018 UNII-4PC054V79P Glyceryl monooleate [NF]

Chemical Function

No specific technical function Fragrance Anti-static agent Softener and conditioner

Regulatory Lists

inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides inert_ingredient; non_food_use; Pesticides IFRA Transparency IFRA Transparency food_additive; Substances Added to Food (formerly EAFUS) (2/2019) SCIL (9/2019) SCIL (9/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in food safety data.

SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Glyceryl monooleate (GMO)
E Number
E471-GMO
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
emulsifier
View full food safety profile →

Frequently Asked Questions

Is Glyceryl Oleate safe in cosmetics?

Glyceryl Oleate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Glyceryl Oleate allowed in the EU?

Glyceryl Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Oleate do in cosmetics?

Glyceryl Oleate functions as: Emollient, Emulsifying, Skin Conditioning. It is classified as a Emollient in our database. CAS number: 25496-72-4.

Is Glyceryl Oleate used outside cosmetics?

Glyceryl Oleate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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